Product Details
Product Name:
BI 99179 |
CAS No.:
1291779-76-4 |
Supply Ability:
10g |
Release date:
2024/11/18 |
Product Introduction
Bioactivity
Name | BI 99179 |
Description | BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1]. |
In vitro | BI 99179 is potent in mouse hypothalamic N-42 cells with an IC50 of 0.6 μM and shows no significant LDH release in cytotoxicity assays up to 30 μM[1]. |
In vivo | BI 99179 exhibits an excellent pharmacokinetic profile following oral administration at a dose of 4 mg/kg in male Han/Wistar rats, showcasing a half-life (t1/2) of 3.0 hours[1]. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | BI 99179 | BI-99179 |
Inhibitors Related | Betulin | Fatostatin hydrobromide | Trimetazidine dihydrochloride | Pyrazinamide | A-769662 | VY-3-135 | Orlistat | trans-Chalcone | TVB-3664 | L-Carnitine | Lycorine | FASN-IN-1 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
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Price |
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$0.00/100MG |
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HangZhou RunYan Pharma Technology Co.,LTD.
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VIP5Y
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