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Balsalazide
Price | Get Latest Price | ||
Package | 1kg | 25kg | 100kg |
Min. Order: | 1kg |
Supply Ability: | 20tons |
Update Time: | 2025-02-21 |
Product Details
Product Name: Balsalazide | CAS No.: 80573-04-2 |
Min. Order: 1kg | Purity: 99% |
Supply Ability: 20tons | Release date: 2025/02/21 |
Product Description
Product Name: Balsalazide
Synonyms:
5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-benzoicaci(e;BALSALZIDE
DISODIUM;BALSALAZIDE SODIUM;BALSALAZIDE;balsalazido;BALSALAZIDE
DISODIUM
SALT;(E)-5-[[4-[[(2-Carboxyethyl)amino]-carbonyl]phenyl]azo-2-hydroxybenzoic
acid;Benzoic acid,
5-((1E)-(4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-
CAS: 80573-04-2
MF: C17H15N3O6
MW: 357.32
EINECS: 617-116-8
Melting point: 254-255°C
Boiling point: 729.6±60.0 °C
Density: 1.44±0.1 g/cm3
Storage temp.: -20°C Freezer
Appearance: Yellow to Beige powder
Description:
Balsalazide
is a prodrug form of 5-aminosalicylic acid (5-ASA; ). It is cleaved by
bacterial azoreductases in the intestinal lumen to release 5-ASA.
Balsalazide (600 mg per day) decreases IL-2 levels and increases IL-6
levels in the serum and colonic mucosa membrane, as well as decreases
micro- and macroscopic colonic damage, in a rat model of colitis induced
by 2,4-dinitrochlorobenzene (DNCB). Formulations containing balsalazide
have been used in the treatment of ulcerative colitis.
Uses:
An
analogue of Sulfa salazine (S699084). A prodrug of 5-aminosalicylic
acid where carrier molecule is 4-aminobenzoyl-β-alanine.
Anti-inflammatory (gastrointestinal).
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- Since: 1996-07-16
- Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.