Anatibant 2HCl NEW
| Price | $350 | $970 | $1200 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Anatibant 2HCl | CAS No.: 209788-45-4 |
| Purity: 99.71% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Anatibant 2HCl |
| Description | Anatibant 2HCl is a small molecule bradykinin B2 receptor antagonist for the treatment of neurological disorders and may be used in the study of brain injury. |
| In vivo | Anatibant (3.0 mg/kg b.w.; Subcutaneous Injection; Male C57/Bl6 mice (CCI)) was administrated as a subcutaneous bolus 15 min and 8h after TBI. ICP was measured 3, 6, and 10 h after injury, and contusion volume was quantified 24 h after trauma. Our data demonstrate a significant reduction of ICP (16.6+/-1.67 mmHg vs. 24.40+/-3.58 mmHg; n=6; p=0.002) and of contusion volume 24 h after trauma (28.28+/-5.18 mm3 vs. 35.0+/-3.32 mm3 n=7; p=0.003) in treated mice. Therefore we conclude, that inhibition of bradykinin B2 receptors seems to be a promising treatment option, and might therefore be investigated in clinical trials for the treatment of TBI.[1] |
| Storage | Shipping with blue ice. |
| Solubility Information | DMSO : 55 mg/mL (70.1 mM) |
| Keywords | Anatibant 2HCl | Anatibant |
| Inhibitors Related | Safotibant | [Des-Arg9]-Bradykinin acetate | B-Raf IN 14 | Lys-Bradykinin acetate(342-10-9 free base) | (Hyp3)-Bradykinin acetate | MK-0686 | ELN-441958 | Sar-[D-Phe8]-des-Arg9-Bradykinin acetate | 5-Hydroxy-1-methylhydantoin | Lys-[Des-Arg9]Bradykinin acetate |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1670.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
| $0.00/1kg |
VIP2Y
|
Sichuan HongRi Pharma-Tech Co.,Ltd
|
2023-09-25 | |
| $195.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-23 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY