ALK-IN-26 NEW
| Price | $35 | $79 | $123 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-17 |
Product Details
| Product Name: ALK-IN-26 | CAS No.: 2447607-85-2 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2024/11/17 |
Product Introduction
Bioactivity
| 名稱 | ALK-IN-26 |
| 描述 | ALK-IN-26 is an ALK inhibitor with potential anticancer activity, demonstrating antiproliferative effects against glioblastoma and inducing apoptosis, autophagy, and necrosis. |
| 體外活性 | In GL261 cells, ALK-IN-26 (0.5 μM, 1.0 μM, 2.0 μM; 24 hours, 48 hours, 72 hours) induced apoptosis of glioblastoma in a concentration- and time-dependent manner, and resulted in cells (24.5%) entering the S phase when treated with 1 μM for 72 hours, but barely proceeding to the G2/M phase[1]. |
| 體內(nèi)活性 | In male C57BL/6J mice, ALK-IN-26 (5 mg/kg; i.v.; single dose) could be rapidly absorbed (Tmax = 0.58 hours) with an acceptable half-life (T1/2 = 3.55 hours) and bioavailability (F = 38.4%)[1]. |
| 存儲(chǔ)條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 關(guān)鍵字 | ALKIN26 |
| 相關(guān)產(chǎn)品 | Alectinib hydrochloride | Lorlatinib | SB-431542 | DMH-1 | RepSox | Crizotinib | Ceritinib | LDN-193189 2HCl | A 83-01 | ALK-IN-1 |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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