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Postion:Product Catalog >AG-636
AG-636
  • AG-636

AG-636 NEW

Price $68 $163 $263
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: AG-636 CAS No.: 1623416-31-8
Purity: 99.19% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAG-636
DescriptionAG-636 is a potent, reversible, and selective DHODH inhibitor with an IC50 of 17 nM and is orally active. It demonstrates strong anticancer effects.
In vitroAG-636, in cancer cell lines of hematologic versus solid tumor origin.?Differential AG-636 activity translated to the in vivo setting, with complete tumor regression observed in a lymphoma model
In vivoAG-636 (10-100 mg/kg; oral gavage; twice daily; for 14 days) treatment significantly inhibits tumor growth in the OCILY19 DLBCL tumor xenograft model.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 31.25 mg/mL (91.01 mM), Sonication is recommended.
Keywordsinhibit | oral | reversible | DHODH | anticancer | AG-636 | AG636 | Inhibitor | Dihydroorotate Dehydrogenase | DNA/RNA Synthesis | AG 636
Inhibitors RelatedRifampicin | 5-Fluorouracil | Rotenone | Mycophenolate Mofetil | Ribavirin | Guanidine hydrochloride | 2,4-D | Acyclovir | Thymidine | Isomalt | Temozolomide | Folic acid
Related Compound LibrariesDNA Damage & Repair Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Orally Active Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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