AG-636 NEW
Price | $68 | $163 | $263 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: AG-636 | CAS No.: 1623416-31-8 |
Purity: 99.19% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | AG-636 |
Description | AG-636 is a potent, reversible, and selective DHODH inhibitor with an IC50 of 17 nM and is orally active. It demonstrates strong anticancer effects. |
In vitro | AG-636, in cancer cell lines of hematologic versus solid tumor origin.?Differential AG-636 activity translated to the in vivo setting, with complete tumor regression observed in a lymphoma model |
In vivo | AG-636 (10-100 mg/kg; oral gavage; twice daily; for 14 days) treatment significantly inhibits tumor growth in the OCILY19 DLBCL tumor xenograft model. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 31.25 mg/mL (91.01 mM), Sonication is recommended. |
Keywords | inhibit | oral | reversible | DHODH | anticancer | AG-636 | AG636 | Inhibitor | Dihydroorotate Dehydrogenase | DNA/RNA Synthesis | AG 636 |
Inhibitors Related | Rifampicin | 5-Fluorouracil | Rotenone | Mycophenolate Mofetil | Ribavirin | Guanidine hydrochloride | 2,4-D | Acyclovir | Thymidine | Isomalt | Temozolomide | Folic acid |
Related Compound Libraries | DNA Damage & Repair Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Orally Active Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$2500.00/100mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
$47.00/5mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
$0.00/1g |
VIP4Y
|
Wuhan Nutra Biotechnology Co.,Ltd
|
2021-05-24 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY