Atenolol
| Price | $10 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 20t |
| Update Time: | 2021-10-29 |
Product Details
| Product Name: Atenolol | CAS No.: 29122-68-7 |
| EC-No.: 249-451-7 | Min. Order: 1KG |
| Purity: 99％ | Supply Ability: 20t |
| Release date: 2021/10/29 |
| Pharmacological Affects | Atenolol ,also known as atenolol, Aten Yue Er, tamoxifen, downhill Ling blood pressure, Tenormin, blood pressure Ling, is a long-acting cardioselective β1-adrenergic blockers, without intrinsic sympathomimetic activity or membrane stability.The atenolol,s retardation for β1 adrenaline receptors is similar with metoprolol, propranolol and nadolol , which is 1/6 times for pindolol and timolol. But, it does not inhibit the effect of the isoproterenol bronchodilator.When administered in small doses, it does not like non-selective β-adrenergic blockers as aggravated hypoglycemia induced hypertensive crisis, peripheral circulatory impairment or patients with obstructive airways disease worsening airway function and so on. However, When administered in large doses, atenolol also can decrease asthma or chronic obstructive pulmonary disease, airway function. Atenolol, as a long-term treatment of hypertension, also were reported for affecting airway function. Thus, despite atenolol heart selection, chronic obstructive pulmonary disease patients can only use small doses, but also should be given a sufficient amount of β1-adrenergic receptor agonists. Oral F is 46%~60%, Tmax about 2~4 h, Mainly unchanged since the urine excretion, T1/2 of 6~7 h. Hemodialysis can clear the goods. Rapidly absorbed from the gastrointestinal tract, but not exclusively.The rest of the body is excreted in the stool. Food can reduce the F, fasting and after meals AUC decreased by 20%. Distribution of the central nervous system is relatively few. The ratio of brain tissue to blood concentration was 0.1:1. Easy to achieve in the placenta and the maternal plasma concentrations of same. PPB is less than 5%, Vd is 50~75 L. Atenolol is not metabolized by the liver, most of the drug is excreted from the body in urine, renal insufficiency in patients with T1/2 was significantly prolonged. Patients with renal failure range of T1/2 was 10~28 h, or even up to 100 h. Results at 24 h after, the discharge from the urine of the drug can be reduced by 29%. The T1/2 of patients with hyperthyroidism was significantly shortened, 4.2h. |
Our Advantages
1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
4.Quick and clear response to customers questions.
Warm after sale service, we will help to solve the problems in your usage.
5.We could make our price discount if you place a substantial order with us.
FAQ
1. What's your payment terms?
T/T or L/C, D/P,D/A,WU,MG.
2. What's your delivery time?
Usually we will arrange the shipment in 7 -15 days.
3. How about the packing?
Usually we provide the packing as 25 kg / bag or carton. Of course, if you have special requirements on them, we will according to you.
4. When can I Get Reply?
Our Area sales manager will contact you as soon as possible in 24 hours one working day!
5. How about the validity of the products?
According to the products you ordered.
6. What documents you provide?
Usually, we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.
7. What certificate you can provide?
According to different kinds of product, we have various certificates like:Halal,Kosher,Haccp,GMP,Iso,Organic Certificate
8. What is loading port?
Usually is Shanghai,Qingdao or Tianjin.
Whatsapp:+86-15832105118
E-mail:info01@byyq-cn.com
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China- Since: 2012-03-20
- Address: Building17,Zhuoda Shanghe original community,No.3 Zhaoling North Road, Xinhua District, Shijiazhuang