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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Angiogenesis>HIF inhibitor>2-Methoxyestradiol
2-Methoxyestradiol
  • 2-Methoxyestradiol
  • 2-Methoxyestradiol
  • 2-Methoxyestradiol

2-Methoxyestradiol

Price Get Latest Price
Package 1kg 25kg
Min. Order: 1kg
Supply Ability: 650KG
Update Time: 2025-03-28

Product Details

Product Name: 2-Methoxyestradiol CAS No.: 362-07-2
Min. Order: 1kg Purity: 99%
Supply Ability: 650KG Release date: 2025/03/28

?2-Methoxyestradiol | Oral-Active Antiangiogenic Agent & Endogenous Metabolite | ≥99% Purity? ????


?? ?Product Overview?

2-Methoxyestradiol is a ?naturally occurring estrogen metabolite? with potent antitumor and antiangiogenic properties?12. It inhibits tumor growth by suppressing hypoxia-inducible factor-1α (HIF-1α) and inducing cancer cell apoptosis?15. Widely used in oncology research and drug development, it also serves as a reference standard in metabolic disorder studies?23.


?Key Advantages?

?? ?Feature??? ?Specification/Effect?
?≥99% HPLC/GC-MS Purity?Validated per USP/EP protocols?12
?Oral Bioavailability?Demonstrated in preclinical models?15
?Low Cytotoxicity?Selective tumor targeting (IC50 <1 μM)?25
?Stability Assurance?24-month shelf life at -20°C?24

?? ?Applications?

  • ?Anticancer Drug Development?

    : Targets breast, prostate, and ovarian cancers via HIF-1α inhibition?15.

  • ?Angiogenesis Research?

    : Suppresses tumor vascularization in preclinical models?12.

  • ?Metabolic Studies?

    : Analyzed as an endogenous biomarker for estrogen metabolism?23.

  • ?Neuroprotection?

    : Investigated for mitigating oxidative stress in neurodegenerative diseases?45.


?? ?Quality Certifications?

  • ?GMP Compliance?

    : Manufactured in ISO 9001-certified facilities?24.

  • ?Batch-Specific COA?

    : Includes NMR, FTIR, and mass spectrometry validation?12.

  • ?Residual Solvents?

    : <10 ppm (meets ICH Q3C guidelines)?24.


?? ?Market Trends?

The ?global anticancer drug market? is projected to reach ?$300B by 2030?, driven by demand for targeted therapies?6. Angiogenesis inhibitors like 2-Methoxyestradiol account for ?18% of oncology pipeline candidates?, reflecting their therapeutic potential?25.

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Article illustration

Article illustration


Company Profile Introduction

Wuhan Biocar Pharmaceutical Co., Ltd. is a high-tech and innovative enterprise specializing in the research, development, production, and sales of APIs and pharmaceutical intermediates (excluding finished drugs). Located in the heart of Optics Valley Biological City, our company leverages the cutting-edge facilities of the Wuhan University Scientific Research Laboratory and benefits from the region's favorable policies to advance the field of biomedicine. Guided by our business philosophy—"Driven by market demand, powered by technological innovation, and enabled by e-commerce"—we are committed to delivering biomedical products that are precise, high-quality, fast, and reliable. Our offerings serve pharmaceutical companies, university research institutions, hospital outpatient services, reagent providers, and distributors worldwide.

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