
2-Methoxyestradiol
Price | Get Latest Price | |
Package | 1kg | 25kg |
Min. Order: | 1kg |
Supply Ability: | 650KG |
Update Time: | 2025-03-28 |
Product Details
Product Name: 2-Methoxyestradiol | CAS No.: 362-07-2 |
Min. Order: 1kg | Purity: 99% |
Supply Ability: 650KG | Release date: 2025/03/28 |
?2-Methoxyestradiol | Oral-Active Antiangiogenic Agent & Endogenous Metabolite | ≥99% Purity? ????
?? ?Product Overview?
2-Methoxyestradiol is a ?naturally occurring estrogen metabolite? with potent antitumor and antiangiogenic properties?12. It inhibits tumor growth by suppressing hypoxia-inducible factor-1α (HIF-1α) and inducing cancer cell apoptosis?15. Widely used in oncology research and drug development, it also serves as a reference standard in metabolic disorder studies?23.
? ?Key Advantages?
?≥99% HPLC/GC-MS Purity? | Validated per USP/EP protocols?12 |
?Oral Bioavailability? | Demonstrated in preclinical models?15 |
?Low Cytotoxicity? | Selective tumor targeting (IC50 <1 μM)?25 |
?Stability Assurance? | 24-month shelf life at -20°C?24 |
?? ?Applications?
- ?Anticancer Drug Development?
: Targets breast, prostate, and ovarian cancers via HIF-1α inhibition?15.
- ?Angiogenesis Research?
: Suppresses tumor vascularization in preclinical models?12.
- ?Metabolic Studies?
: Analyzed as an endogenous biomarker for estrogen metabolism?23.
- ?Neuroprotection?
: Investigated for mitigating oxidative stress in neurodegenerative diseases?45.
?? ?Quality Certifications?
- ?GMP Compliance?
: Manufactured in ISO 9001-certified facilities?24.
- ?Batch-Specific COA?
: Includes NMR, FTIR, and mass spectrometry validation?12.
- ?Residual Solvents?
: <10 ppm (meets ICH Q3C guidelines)?24.
?? ?Market Trends?
The ?global anticancer drug market? is projected to reach ?$300B by 2030?, driven by demand for targeted therapies?6. Angiogenesis inhibitors like 2-Methoxyestradiol account for ?18% of oncology pipeline candidates?, reflecting their therapeutic potential?25.
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