(±)-Praeruptorin A NEW
| Price | $44 | $77 | $127 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-17 |
Product Details
| Product Name: (±)-Praeruptorin A | CAS No.: 73069-25-7 |
| Purity: 99.73% | Supply Ability: 10g |
| Release date: 2024/11/17 |
Product Introduction
Bioactivity
| 名稱 | (±)-Praeruptorin A |
| 描述 | 1. (±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation 2. Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis. 3. Praeruptorin A and praeruptorin C can significantly upregulate multidrug resistance-associated protein 2 expression via the constitutive androstane receptor-mediated pathway in vitro, and this should be taken as an herb-drug interaction. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 70 mg/mL (181.2 mM) Ethanol : Soluble Pyridine, Methanol, etc. : Soluble |
| 關鍵字 | Ca channels | Ca2+ channels | (±)-Praeruptorin A | inhibit | Calcium Channel | Inhibitor | (±)Praeruptorin A | (±) Praeruptorin A |
| 相關庫 | 抗癌天然產(chǎn)物庫 | 中藥單體化合物庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 植物來源化合物庫 | 神經(jīng)保護化合物庫 | 高通量篩選天然產(chǎn)物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 離子通道庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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