β,β-Dimethylacrylshikonin NEW
| Price | Get Latest Price |
| Package | 1removed |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-26 |
Product Details
| Product Name: β,β-Dimethylacrylshikonin | CAS No.: 24502-79-2 |
| Purity: 98.86% | Supply Ability: 10g |
| Release date: 2025/06/26 |
Product Introduction
Bioactivity
| Name | β,β-Dimethylacrylshikonin |
| Description | 1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significantly suppressed tumor growth of the HCT-116 xenograft. (b) Dimethylacrylshikonin significantly suppressed the growth of H(22) transplantable hepatoma, and induced the activation of caspase-3 . (c) Dimethylacrylshikonin inhibited growth of gastric cancer SGC-791 cells by inducing ERK signaling pathway. 2. Dimethylacrylshikonin inhibits the proliferation of MCF-7 cells in vitro by inducing apoptosis through the downregulation of Bcl-2, upregulation of Bax and partial inactivation of the NF-κB pathway. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
| Solubility Information | DMSO : 3.70 mg/mL (9.99 mM), Sonication is recommended. |
| Keywords | β,β-Dimethylacrylshikonin | β,βDimethylacrylshikonin | β,β Dimethylacrylshikonin | Isoarnebin I | Inhibitor | inhibit | HIFProlylHydroxylase | HIF-1α | HIF/HIFProlylHydroxylase | HIF/HIF ProlylHydroxylase | HIF Prolyl-Hydroxylase | HIF ProlylHydroxylase | HIF | ERK | beta,beta-Dimethylacrylshikonin | beta, beta-Dimethylacrylshikonin | b,b-Dimethylacrylshikonin | b, b-Dimethylacrylshikonin |
| Inhibitors Related | TBHQ | Deferoxamine Mesylate | Lidocaine | Astragaloside IV | Glucosamine | Hydroxycitric acid tripotassium hydrate | Lidocaine hydrochloride | Tauroursodeoxycholate | Chloramphenicol | Nisin Z | Albendazole | Glucosamine sulfate |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Polyphenolic Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Pain-Related Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library for HTS | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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