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BOC Sciences
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Product Name:(4E)-SUN9221
CAS:222318-55-0
Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
MedChemexpress LLC
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021-58955995 |
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| Products Intro: |
Product Name:Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 1-[4-[4-(4-fluorobenzoyl)-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-, 4-oxime, (4E)-
CAS:222318-55-0
Purity:1440RMB/1mg Package:>98%
|
Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 1-[4-[4-(4-fluorobenzoyl)-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-, 4-oxime, (4E)- manufacturers
- (4E)-SUN9221
-
- $1800.00 / 5mg
-
2024-11-20
- CAS:222318-55-0
- Min. Order:
- Purity: 97.79%
- Supply Ability: 10g
- (4E)-SUN9221
-
- $1800.00 / 5mg
-
2024-11-20
- CAS:222318-55-0
- Min. Order:
- Purity: 97.79%
- Supply Ability: 10g
|
| | Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 1-[4-[4-(4-fluorobenzoyl)-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-, 4-oxime, (4E)- Basic information |
| Product Name: | Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 1-[4-[4-(4-fluorobenzoyl)-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-, 4-oxime, (4E)- | | Synonyms: | Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 1-[4-[4-(4-fluorobenzoyl)-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-, 4-oxime, (4E)-;(4E)-SUN9221;(4E)-SUN-9221,(4E)SUN9221,(4E) SUN9221 | | CAS: | 222318-55-0 | | MF: | C25H31FN4O3 | | MW: | 454.5370432 | | EINECS: | | | Product Categories: | | | Mol File: | 222318-55-0.mol | ![Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 1-[4-[4-(4-fluorobenzoyl)-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-, 4-oxime, (4E)- Structure](CAS/20180601/GIF/222318-55-0.gif) |
| | Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 1-[4-[4-(4-fluorobenzoyl)-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-, 4-oxime, (4E)- Chemical Properties |
| Boiling point | 661.7±55.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 11.20±0.20(Predicted) |
| | Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 1-[4-[4-(4-fluorobenzoyl)-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-, 4-oxime, (4E)- Usage And Synthesis |
| Uses | (4E)-SUN9221 is a potent antagonist of α1-adrenergic receptor and 5-HT2 receptor, with antihypertensive and anti-platelet aggregation activities. | | in vivo | (4E)-SUN9221 (1, 3, 10 mg/kg, p.o.) reduces the blood pressure in a dose-dependent manner in conscious spontaneously hypertensive rats (SHR). (4E)-SUN9221 (3 mg/kg) exhibits antihypertensive activity in SHR[1]. | | IC 50 | 5-HT2 Receptor; α1 | | References | [1] Mizuno A, et al. Synthesis and pharmacological evaluation of pyrroloazepine derivatives as potent antihypertensive agents with antiplatelet aggregation activity. Chem Pharm Bull (Tokyo). 1999 Feb;47(2):246-56. DOI:10.1248/cpb.47.246 |
| | Pyrrolo[2,3-c]azepine-4,8(1H,5H)-dione, 1-[4-[4-(4-fluorobenzoyl)-1-piperidinyl]butyl]-6,7-dihydro-7-methyl-, 4-oxime, (4E)- Preparation Products And Raw materials |
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