| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:ABI-231 HCl
CAS:2635953-17-0
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
|
Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-, hydrochloride (1:1) manufacturers
- ABI-231 HCl
-
- $1980.00 / 50mg
-
2025-04-27
- CAS:2635953-17-0
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-, hydrochloride (1:1) Basic information |
| | Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-, hydrochloride (1:1) Chemical Properties |
| | Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-, hydrochloride (1:1) Usage And Synthesis |
| Uses | Sabizabulin hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. Sabizabulin hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of Sabizabulin hydrochloride shows it has a low risk of potential side effects[1]. | | References | [1] Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1 H-Indol-3-yl)-1 H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin DOI:10.1021/acs.jmedchem.9b00706 |
| | Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-, hydrochloride (1:1) Preparation Products And Raw materials |
|