4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Suppliers list

Company Name:	TargetMol Chemicals Inc.
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Products Intro:	Product Name:Thalidomide-NH-PEG1-NH2 hydrochloride CAS:2154342-56-8 Purity:97.13% Package:1mg;37USD\|5mg;83USD\|10mg;119USD

Company Name:	TargetMol Chemicals Inc.
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Products Intro:	Product Name:Thalidomide-NH-PEG1-NH2 hydrochloride；4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl CAS:2154342-56-8 Package:100 mg；200 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Xian confluore Biological Technology Co., Ltd.
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Products Intro:	Product Name:Pomalidomide-NH-PEG1-amine hydrochloride CAS:2154342-56-8 Purity:>99.00% Package:1g

Company Name:	Aladdin Scientific
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Products Intro:	Product Name:Pomalidomide 4'-PEG1-amine hydrochloride CAS:2154342-56-8 Purity:>=95%(HPLC) Package:$42.9/5mg;$65.9/10mg;$125.9/25mg;$225.9/50mg;$406.9/100mg;Bulk package Remarks:95%(HPLC)

Company Name:	ChemShuttle, Inc.
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Products Intro:	Product Name:4-((2-(2-aminoethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride CAS:2154342-56-8 Purity:95% Package:5mg;25mg;100mg;500mg;1g;5g;10g;25g;50g;100g;250g;500g;kg…

4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl manufacturers

4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Basic information

Product Name:	4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
Synonyms:	4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;Pomalidomide-NH-PEG1-amine hydrochloride;3-dione HCl;4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2;6-dioxopiperidin-3-yl)isoindoline-1;Thalidomide-NH-PEG1-NH2 hydrochloride;Thalidomide-NH-PEG1-NH2 TFA;inhibit,Thalidomide-NH-PEG-1-NH2 hydrochloride,ThalidomideNHPEG1NH2 hydrochloride,Inhibitor,E3 Ligase Ligand-Linker Conjugates,Thalidomide NH PEG1 NH2 hydrochloride
CAS:	2154342-56-8
MF:	C17H21ClN4O5
MW:	396.83
EINECS:
Product Categories:
Mol File:	2154342-56-8.mol

4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Chemical Properties

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MSDS Information

4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Usage And Synthesis

Uses	Thalidomide-NH-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Biological Activity	Pomalidomide 4'-PEG1-amine is a functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal amine ready for conjugation to a target protein ligand.
IC 50	Cereblon
storage	Store at -20°C
References	[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326 [2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Preparation Products And Raw materials

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