N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride manufacturers
- M8-B Hydrochloride
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- $48.00 / 5mg
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2024-11-19
- CAS:883976-12-3
- Min. Order:
- Purity: 99.33%
- Supply Ability: 10g
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| N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Basic information |
Product Name: | N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride | Synonyms: | M8-B hydrochloride;N-(2-Aminoethyl)-N-(4-(benzyloxy)-3-methoxybenzyl)thiophene-2-carboxamide hydrochloride;N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride;2-Thiophenecarboxamide, N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, monohydrochloride;M8-B;M8-B hydrochloride >=98% (HPLC);M8 B Hydrochloride,M-8-B Hydrochloride,M8B Hydrochloride;M8 B HCl | CAS: | 883976-12-3 | MF: | C22H25ClN2O3S | MW: | 432.9635 | EINECS: | | Product Categories: | | Mol File: | 883976-12-3.mol | ![N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Structure](CAS/20180703/GIF/883976-12-3.gif) |
| N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Chemical Properties |
storage temp. | 2-8°C | solubility | H2O: soluble2mg/mL, clear (warmed) | form | powder | color | white to beige | Water Solubility | H2O: 2mg/mL, clear (warmed) |
| N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Usage And Synthesis |
Description | M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin , or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively). It displays no effect at other TRP channels. M8-B decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 KO mice. | Uses | M8 B Hydrochloride is a channel blocker of cold receptor TRPM8. | storage | Store at +4°C |
| N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Preparation Products And Raw materials |
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