| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:CDK9-IN-11
CAS:2748368-15-0
Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800
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| | 1H-Pyrazole-1-carboxylic acid, 5-cyclobutyl-3-[[2-(4-hydroxyphenyl)acetyl]amino]-, 1,1-dimethylethyl ester Basic information |
| | 1H-Pyrazole-1-carboxylic acid, 5-cyclobutyl-3-[[2-(4-hydroxyphenyl)acetyl]amino]-, 1,1-dimethylethyl ester Chemical Properties |
| density | 1.27±0.1 g/cm3(Predicted) | | form | Solid | | pka | 9.82±0.15(Predicted) | | color | White to off-white |
| | 1H-Pyrazole-1-carboxylic acid, 5-cyclobutyl-3-[[2-(4-hydroxyphenyl)acetyl]amino]-, 1,1-dimethylethyl ester Usage And Synthesis |
| Uses | CDK9-IN-11 is a potent CDK9 inhibitor. CDK9-IN-11 is the ligand for the PROTAC CDK9 Degrader-1 (HY-103628)[1]. | | IC 50 | CDK9 | | References | [1] Robb CM, et al. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC). Chem Commun (Camb). 2017 Jul 4;53(54):7577-7580. DOI:10.1039/c7cc03879h |
| | 1H-Pyrazole-1-carboxylic acid, 5-cyclobutyl-3-[[2-(4-hydroxyphenyl)acetyl]amino]-, 1,1-dimethylethyl ester Preparation Products And Raw materials |
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