Company Name: |
TargetMol Chemicals Inc.
|
Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:CG0009 CAS:944744-57-4 Package:50mg/RMB 15300;100mg/RMB 19500;25mg/RMB 11700
|
CG-0009 manufacturers
- CG0009
-
- $2180.00 / 50mg
-
2024-10-28
- CAS:944744-57-4
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| CG-0009 Basic information |
| CG-0009 Chemical Properties |
| CG-0009 Usage And Synthesis |
Description | CG0009 is a potent and selective a Glycogen Synthase Kinase 3 (GSK3) inhibitor. CG0009, inhibits proliferation, induces apoptosis cell death, and activates the p53-Bax pathway in breast cancer cells, predominantly via cyclin D1 depletion. CG0009 induces significant growth inhibition and cell death in breast cancer cell lines, with a wide range of IC50 values (between 0.49 (MCF7) and 11 μM (NCI/ADR-RES and BT549)). CG0009 inhibits breast cancer cell growth through cyclin D1 depletion and p53 activation, and may thus offer an innovative therapeutic approach for breast cancers resistant to hormone-based therapy. |
| CG-0009 Preparation Products And Raw materials |
|