| Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
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| Tel: |
+86-156-80926068 +86-15680926068 |
| Email: |
1924344760@qq.com |
| Products Intro: |
Product Name:Boc-NH-PEG4-C2-Boc
CAS:2138484-13-4
Purity:98% HPLC Package:10MG;25MG;50MG;100MG;1G;5G Remarks:For customers outside China,please use the website:www.confluore.com
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Boc-NH-PEG4-C2-Boc
CAS:2138484-13-4
Purity:95% Package:2mg
|
5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1,17-bis(1,1-dimethylethyl) ester manufacturers
- Boc-NH-PEG4-C2-Boc
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- $0.00 / 1g
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2024-03-25
- CAS:2138484-13-4
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1,17-bis(1,1-dimethylethyl) ester Basic information |
| Product Name: | 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1,17-bis(1,1-dimethylethyl) ester | | Synonyms: | 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1,17-bis(1,1-dimethylethyl) ester;Boc-NH-PEG4-C2-Boc | | CAS: | 2138484-13-4 | | MF: | C20H39NO8 | | MW: | 421.53 | | EINECS: | | | Product Categories: | | | Mol File: | 2138484-13-4.mol |  |
| | 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1,17-bis(1,1-dimethylethyl) ester Chemical Properties |
| Boiling point | 497.2±40.0 °C(Predicted) | | density | 1.053±0.06 g/cm3(Predicted) | | pka | 12.23±0.46(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1,17-bis(1,1-dimethylethyl) ester Usage And Synthesis |
| Biological Activity | Boc-NH-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1,17-bis(1,1-dimethylethyl) ester Preparation Products And Raw materials |
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