| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
|
| Tel: |
025-85560043 13675144456 |
| Email: |
sean.lv@synzest.com |
| Products Intro: |
Product Name:Ethyl 4-(3-oxoisothiazol-2(3H)-yl)benzoate
CAS:26530-26-7
Purity:95%HPLC Package:500mg;1g;5g;10g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Ethyl 4-(3-oxoisothiazol-2(3H)-yl)benzoate
CAS:26530-26-7
Purity:95% Package:2mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:KM04416
CAS:26530-26-7
Purity:99.88% Package:2mg/RMB 698
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:ethyl 4-(3-oxo-2(3H)-isothiazolyl)benzoate
CAS:26530-26-7
|
Benzoic acid, 4-(3-oxo-2(3H)-isothiazolyl)-, ethyl ester manufacturers
- KM04416
-
- $67.00 / 2mg
-
2025-05-30
- CAS:26530-26-7
- Min. Order:
- Purity: 99.88%
- Supply Ability: 10g
|
| | Benzoic acid, 4-(3-oxo-2(3H)-isothiazolyl)-, ethyl ester Basic information |
| | Benzoic acid, 4-(3-oxo-2(3H)-isothiazolyl)-, ethyl ester Chemical Properties |
| Melting point | 142-144 °C(Solv: toluene (108-88-3)) | | Boiling point | 404.8±47.0 °C(Predicted) | | density | 1.328±0.06 g/cm3(Predicted) | | pka | -3.20±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | Benzoic acid, 4-(3-oxo-2(3H)-isothiazolyl)-, ethyl ester Usage And Synthesis |
| Uses | KM04416, an isothiazolone derivative, is a potent glycerol-3-phosphate dehydrogenase (GPD2) inhibitor. KM04416 significantly inhibits PNT1A cell proliferation[1][2]. | | References | [1] Sehyun Oh, et al. Non-bioenergetic roles of mitochondrial GPD2 promote tumor progression. Theranostics. 2023 Jan 1;13(2):438-457. DOI:10.7150/thno.75973
[2] Gurmit Singh, et al. Mitochondrial FAD-linked Glycerol-3-phosphate Dehydrogenase: A Target for Cancer Therapeutics. Pharmaceuticals (Basel). 2014 Feb 11;7(2):192-206. DOI:10.3390/ph7020192 |
| | Benzoic acid, 4-(3-oxo-2(3H)-isothiazolyl)-, ethyl ester Preparation Products And Raw materials |
|