| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:8-epi-Prostaglandin F2α
CAS:27415-26-5
Purity:>99% Package:10Mg,25Mg,50Mg
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| Company Name: |
Chemsky (shanghai) International Co.,Ltd
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| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:8-epi-Prostaglandin F2α-d9;(5Z,8β,9α,11α,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic Acid-d9;
7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-Heptenoic Acid-d9; 15(S)-8-Iso-PGF2α; 15-F2t-IsoP-d9; 15-F2t-Isoprostane-d9; 8-Isoprostaglandin F2α-d9; 8-epi-PGF2α-d9; 8-iso-Prostaglandin F2α-d9; Isoprostaglandin F2α type-III-d9; 8-Iso-PGF2α-d9
CAS:27415-26-5
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:8-epi-Prostaglandin F2α
CAS:27415-26-5
Purity:> 95% Remarks:A metabolite of PGF2α. Prostaglandin F2α is a naturally occurring prostaglandin used in medicine to
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| | 11BETA-PROSTAGLANDIN E1 Basic information |
| | 11BETA-PROSTAGLANDIN E1 Chemical Properties |
| Boiling point | 531.0±50.0 °C(Predicted) | | density | 1.153±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: 3 mg/ml | | form | A crystalline solid | | pka | 4.76±0.10(Predicted) | | color | White to off-white |
| | 11BETA-PROSTAGLANDIN E1 Usage And Synthesis |
| Description | 8-iso PGF2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2α level of about 150 pg/ml in normal volunteers. In normal human urine, 8-iso PGF2α levels are about 180-200 pg/mg of creatinine. 8-iso PGF2α is a weak TP receptor agonist in vascular smooth muscle. Conversely, 8-iso PGF2α inhibits platelet aggregation induced by U-46619 (10−6 M) and I-BOP (3 x 10−7 M) with IC50 values of 1.6 x 10−6 M and 1.8 x 10−6 M, respectively. | | Description | 8-iso Prostaglandin F2α (8-iso PGF2α) is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2α level of about 150 pg/ml in normal volunteers. In normal human urine, 8-iso PGF2α levels are about 180-200 pg/mg of creatinine. 8-iso PGF2α is a weak TP receptor agonist in vascular smooth muscle. Conversely, 8-iso PGF2α inhibits platelet aggregation induced by U-46619 (10−6 M) and I-BOP (3 x 10−7 M) with IC50 values of 1.6 x 10−6 M and 1.8 x 10−6 M, respectively.
8-iso Prostaglandin F2α MaxSpec® standard is a quantitative grade standard of 8-iso Prostaglandin F2α that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 8-iso Prostaglandin F2α MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality. | | Uses | (8-epi-prostaglandin F2a) A major metabolite of PGF2α. A prostaglandin derivative used as a biomarker in the diagnosis and treatment of cardiovascular-related diseases as well as biomarkers of total body oxidative stress. | | Uses | A major metabolite of PGF2α. A prostaglandin derivative used as a biomarker in the diagnosis and treatment of cardiovascular-related diseases as well as biomarkers of total body oxidative stress. | | Definition | ChEBI: A prostanoid that is prostaglandin F2alpha having inverted stereochemistry at the 8-position. |
| | 11BETA-PROSTAGLANDIN E1 Preparation Products And Raw materials |
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