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1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate

1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:MT-3014
CAS:1332727-40-8
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:MT-3014
CAS:1332727-40-8
Package:25mg;1820USD|100mg;3100USD|50mg;2380USD
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Products Intro: Product Name:MT-3014
CAS:1332727-40-8
Package:25mg;1820USD|100mg;3100USD|50mg;2380USD
Company Name: Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd  
Tel: 15317229551
Email: 15151849396@163.com
Products Intro: Product Name:MT-3014
CAS:1332727-40-8
Purity:98% HPLC Package:1g
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:MT-3014
CAS:1332727-40-8
Package:25mg/RMB 12800;100mg/RMB 21500;50mg/RMB 16800

1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate manufacturers

  • MT-3014
  • MT-3014 pictures
  • $1820.00 / 25mg
  • 2024-10-28
  • CAS:1332727-40-8
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate Basic information
Product Name:1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate
Synonyms:1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate;MT-3014;MT3014,MT 3014;2-Propanol, 1-[[2-(7-fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-
CAS:1332727-40-8
MF:C23H25F2N7O
MW:453.49
EINECS:
Product Categories:
Mol File:1332727-40-8.mol
1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate Structure
1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate Chemical Properties
density 1.45±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka14.58±0.29(Predicted)
Safety Information
MSDS Information
1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate Usage And Synthesis
Description

MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively[1]. human PDE 10A|0.062 nM (IC50)|bovine PDE 10A|0.09 nM (IC50)

References

[1]. Koizumi Y, et al. Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety. Bioorg Med Chem. 2019 Jun 19.

1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate Preparation Products And Raw materials
Tag:1-[[2-(7-Fluoro-3-methyl-2-quinoxalinyl)-5-[(3R)-3-fluoro- 1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]-2-methyl-2-propanol Monohydrate(1332727-40-8) Related Product Information