| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:OSI-296
CAS:1175296-94-2
Package:100mg/RMB 23500;50mg/RMB 18300;25mg/RMB 13900
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1(2H)-Pyridinecarboxamide, 4-[6-amino-7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-3-yl]-3,6-dihydro- manufacturers
- OSI-296
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- $3400.00 / 100mg
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2024-10-28
- CAS:1175296-94-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 1(2H)-Pyridinecarboxamide, 4-[6-amino-7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-3-yl]-3,6-dihydro- Basic information |
| | 1(2H)-Pyridinecarboxamide, 4-[6-amino-7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-3-yl]-3,6-dihydro- Chemical Properties |
| Boiling point | 633.0±65.0 °C(Predicted) | | density | 1.482±0.06 g/cm3(Predicted) | | pka | 14.55±0.40(Predicted) |
| | 1(2H)-Pyridinecarboxamide, 4-[6-amino-7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-3-yl]-3,6-dihydro- Usage And Synthesis |
| Description | OSI-296 is a potent and dual inhibitor of cMET and RON kinases with IC50 for cMet = 42 nM and IC50 for sfRon = 200 nM. OSI-206 shows in vivo efficacy in tumor xenografts models upon oral dosing and is well tolerated. OSI-296 also reduced tumour growth in the bone. |
| | 1(2H)-Pyridinecarboxamide, 4-[6-amino-7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-3-yl]-3,6-dihydro- Preparation Products And Raw materials |
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