Compound 7 manufacturers
- HDAC-IN-4
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- $68.00 / 2mg
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2024-10-24
- CAS:1252003-13-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Compound 7 Basic information |
| Product Name: | Compound 7 | | Synonyms: | HDACIN4,HDAC IN 4;Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-9H-pyrido[3,4-b]indol-9-yl)methyl]-;COMPOUND 7 (HCL SALT) | | CAS: | 1252003-13-6 | | MF: | C20H21N3O2 | | MW: | 335.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1252003-13-6.mol |  |
| | Compound 7 Chemical Properties |
| density | 1.28±0.1 g/cm3(Predicted) | | pka | 8.95±0.10(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | Compound 7 Usage And Synthesis |
| Description | HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor that has antitumor activity. | | Uses | HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC50s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity[1]. | | References | [1] Géraldy M, et al. Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated. J Med Chem. 2019 May 9;62(9):4426-4443. DOI:10.1021/acs.jmedchem.8b01936 |
| | Compound 7 Preparation Products And Raw materials |
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