MS0124 manufacturers
- MS0124
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- $329.00 / 1mg
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2024-11-19
- CAS:1197196-63-6
- Min. Order:
- Purity: 99.56%
- Supply Ability: 10g
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| Product Name: | MS0124 | | Synonyms: | MS0124;4-Quinazolinamine, 6,7-dimethoxy-N-(1-methyl-4-piperidinyl)-2-(4-morpholinyl)-;MS0124, 10 mM in DMSO | | CAS: | 1197196-63-6 | | MF: | C20H29N5O3 | | MW: | 387.48 | | EINECS: | | | Product Categories: | | | Mol File: | 1197196-63-6.mol |  |
| | MS0124 Chemical Properties |
| Boiling point | 582.6±60.0 °C(Predicted) | | density | 1.232±0.06 g/cm3(Predicted) | | pka | 8.84±0.70(Predicted) |
| | MS0124 Usage And Synthesis |
| Description | MS0124 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. MS0124 was 34-fold more selective for GLP (IC50 =_x000D_
13 ± 4 nM) over G9a (IC50 = 440 ± 63 nM). G9a-like protein (GLP) and G9a are highly homologous protein lysine methyltransferases (PKMTs) sharing approximately 80% sequence identity in their catalytic domains. GLP and G9a form a heterodimer complex and catalyze mono- and dimethylation of histone H3 lysine 9 and nonhistone substrates |
| | MS0124 Preparation Products And Raw materials |
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