- CVT-10216
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- $43.00 / 1mg
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2024-10-28
- CAS:1005334-57-5
- Min. Order:
- Purity: 98.76%
- Supply Ability: 10g
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| | CVT-10216 Basic information |
| Product Name: | CVT-10216 | | Synonyms: | CVT-10216;3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic acid;GS 455534;3-(((3-(4-(Methylsulfonamido)phenyl)-4-oxo-4H-chromen-7-yl)oxy)methyl)benzoic acid;3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]-benzoic acid;CVT-10216;CVT 10216;CVT10216;CS-1424;Benzoic acid, 3-[[[3-[4-[(methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]- | | CAS: | 1005334-57-5 | | MF: | C24H19NO7S | | MW: | 465.48 | | EINECS: | | | Product Categories: | | | Mol File: | 1005334-57-5.mol |  |
| | CVT-10216 Chemical Properties |
| Boiling point | 714.2±70.0 °C(Predicted) | | density | 1.468±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble to 100 mM in DMSO and to 50 mM in 1eq. NaOH | | form | Powder | | pka | 4.13±0.10(Predicted) | | color | White to off-white |
| | CVT-10216 Usage And Synthesis |
| Uses | 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic Acid is a highly selective reversible aldehyde dehydrogenase 2 (ALDH-2) inhibitor that reduce alcohol and cocaine intake in rats. It also has anxiolytic properties as well as reduces excessive alcohol drinking. | | Biological Activity | CVT-10216 is a selective reversible inhibitor of aldehyde dehydrogenase-2 (ALDH-2), thereby inhibiting dopamine synthesis. CVT-10216 is active in suppressing alcohol and cocaine use, and anxiety.', 'CVT-10216 possesses unequivocal anxiolytic properties. It will not affect the suppression of locomotor activity by mCPP (m-chlorophenylpiperazine). | | storage | Store at +4°C |
| | CVT-10216 Preparation Products And Raw materials |
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