Methane sulfonyl azide manufacturers
- Methane sulfonyl azide
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- $85.00 / 1kg
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2025-06-03
- CAS:1516-70-7
- Min. Order: 10kg
- Purity: 0.99
- Supply Ability: 20tons
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| | Methane sulfonyl azide Basic information |
| Product Name: | Methane sulfonyl azide | | Synonyms: | Methane sulfonyl azide;Methanesulfonic acid azide;N-diazomethanesulfonamide;METHANE SULPHONYLAZIDE;Methylsulfonyl azide | | CAS: | 1516-70-7 | | MF: | CH3N3O2S | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 1516-70-7.mol |  |
| | Methane sulfonyl azide Chemical Properties |
| Melting point | 91-92 °C | | Boiling point | 59-60 °C(Press: 17 Torr) | | density | 1.4361 g/cm3 | | refractive index | 1.4675 | | solubility | sol Et2O, MeOH, MeCN; sparingly sol 95% EtOH, cold H2O. | | Appearance | low-melting white solid or clear, colorless oil |
| | Methane sulfonyl azide Usage And Synthesis |
| Uses | Methane sulfonyl azide is used as a diazo transfer reagent for activated methylene,[1] methine,[1,2] and methyl[3] groups; functionalization of double
and triple bonds. | | Preparation | Preparative Methods of Methane sulfonyl azide: reaction of Methanesulfonyl Chloride with Sodium Azide in MeOH(EtOH)/H2O[1,3] or
acetone[2] (55-61 or 96% yields, respectively). By substituting acetone for methanol, the formation of
MeSO2OMe is avoided and the reagent is obtained in >95% purity. | | storage | Methane sulfonyl azide should be stored in the cold and the dark. Explosive when heated above
130 °C. No experimentalists have reported any difficulty handling MsN3, but proper caution should be used,
as with all azide reagents. Use in a fume hood. | | Purification Methods | Purification of Methane sulfonyl azide: crystallization from ether in dry-ice/acetone or from 95% EtOH at -75 °C; distillation in vacuo. | | References | 1. (a) Taber, D. F.; Ruckle, R. E.; Hennessy, M. J. JOC 1986, 51, 4077. (b) Taber, D. F.; Hennessy, M. J.; Lovey, J. P.
JOC 1992, 57, 436.
2. Danheiser, R. L.; Miller, R. F.; Brisbois, R. G.; Park, S. Z. JOC 1990, 55, 1959.
3. Shatzmiller, S.; Bercovici, S. LA 1992, 877. |
| | Methane sulfonyl azide Preparation Products And Raw materials |
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