SID 487795 manufacturers
- NSC 617145
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- $31.00 / 1mg
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2025-05-28
- CAS:203115-63-3
- Min. Order:
- Purity: 98.31%
- Supply Ability: 10g
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| | SID 487795 Basic information |
| Product Name: | SID 487795 | | Synonyms: | (2,3-Propandiyl-bis(2,3-dichloro)maleimide;1,1′-(2,2-Dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-Pyrrole-2,5-dione;NSC-617145;SID 487795;NSC617145;NSC-617145;NSC 617145;WRN INHIBITOR;WRN inhibitor;1H-Pyrrole-2,5-dione, 1,1'-(2,2-dimethyl-1,3-propanediyl)bis[3,4-dichloro- (9CI);1,1'-(2,2-Dimethylpropane-1,3-diyl)bis(3,4-dichloro-1H-pyrrole-2,5-dione) | | CAS: | 203115-63-3 | | MF: | C13H10Cl4N2O4 | | MW: | 400.04 | | EINECS: | | | Product Categories: | | | Mol File: | 203115-63-3.mol |  |
| | SID 487795 Chemical Properties |
| Boiling point | 451.5±45.0 °C(Predicted) | | density | 1.67±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble3mg/mL, clear (warmed) | | pka | -6.03±0.60(Predicted) | | form | powder | | color | white to light brown |
| | SID 487795 Usage And Synthesis |
| Uses | NSC 617145 is ahelicase inhibitor used in the treatment of Werner syndrome helicase and acts synergistically with Mitomycin C (M371900), an antitumor antibiotic. It is used as antineoplastic. | | Biological Activity | NSC 617145 has an IC50 value of 230nM.', 'NSC 617145 is a potent and cell-permeable inhibitor of Werner syndrome helicase (WRN) th at causes accumulation of double-strand breaks (DSB) and chromosomal abnormalities in cancer cells. | | storage | Store at -20°C |
| | SID 487795 Preparation Products And Raw materials |
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