| Company Name: |
Codow Chemical Co.,Ltd.
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| Tel: |
18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:(S)-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid (TFA salt)
CAS:909725-64-0
Purity:>99% Package:1MG;2.5MG;5MG
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| Company Name: |
Chengdu Dianchun Technology Co., Ltd
|
| Tel: |
400-1166-196 18502815961 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:(S)-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid (TFA salt)
CAS:909725-64-0
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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| | (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Basic information |
| | (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Ethanol: 0.15 mg/ml | | form | A crystalline solid |
| | (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Usage And Synthesis |
| Description | W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 .1 It only weakly binds to S1P1 (Ki = 4.6 μM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.1,2 | | References | 1. Sanna, M.G., Wang, S.K., Gonzalez-Cabrera, P.J., et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo Nat. Chem. Biol. 2(8),434-441(2006).
2. Li, C., Chi, X.X., Xie, W., et al. Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor J. Neurophysiol. 108(5),1473-1483(2012). |
| | (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Preparation Products And Raw materials |
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