(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid Suppliers list

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Email:	ivan@atkchemical.com
Products Intro:	Product Name:(E)-3-[4-[3-(1-adamantyl)-4-hydroxyphenyl]phenyl]prop-2-enoic acid CAS:496868-77-0 Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G

Company Name:	career henan chemical co
Tel:	+86-0371-86658258 +8613203830695
Email:	sales@coreychem.com
Products Intro:	Product Name:(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid CAS:496868-77-0 Purity:98% Package:1KG;1USD\|1KG;1USD

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354 +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:Adarotene CAS:496868-77-0 Purity:99.68% Package:1mg;32USD\|2mg;45USD\|5mg;74USD Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	InvivoChem
Tel:	+1-708-310-1919 +1-13798911105
Email:	sales@invivochem.cn
Products Intro:	Product Name:Adarotene (ST1926) CAS:496868-77-0 Purity:98% Package:10mg Remarks:V6708

Company Name:	TargetMol Chemicals Inc.
Tel:
Email:	support@targetmol.com
Products Intro:	Product Name:Adarotene CAS:496868-77-0 Purity:99.68% Package:1mg;32USD\|2mg;45USD\|5mg;74USD

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid manufacturers

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid
$1.00 / 1KG
2019-09-02
CAS:496868-77-0
Min. Order: 1KG
Purity: 98%
Supply Ability: 1lg; 2kg; 5kg; 10kg; 100kg

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid Basic information

Product Name:	(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid
Synonyms:	Adarotene (ST1926);(E)-3-[4-[3-(1-adamantyl)-4-hydroxyphenyl]phenyl]prop-2-enoic acid;ADAROTENE;ST 1926;ST-1926;ST1926;(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid;Adarotene;ST 1926;ST 1926;ST-1926;ST1926;2-Propenoic acid, 3-(4'-hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-, (2E)-
CAS:	496868-77-0
MF:	C25H26O3
MW:	374.47
EINECS:
Product Categories:
Mol File:	496868-77-0.mol

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid Chemical Properties

Melting point	>240 °C
Boiling point	574.1±50.0 °C(Predicted)
density	1.257
storage temp.	Store at -20°C
solubility	≥37.4 mg/mL in DMSO; insoluble in H2O; ≥10.97 mg/mL in EtOH with gentle warming and ultrasonic
form	solid
pka	-95.54±0.10(Predicted)
color	White to green

Safety Information

MSDS Information

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid Usage And Synthesis

Uses	Adarotene has been found to have antitumor activity against different types of cancer, including acute myeloid leukemia, primary effusion lymphoma, prostate cancer and glioma. It may also be useful in treating acute lung injury through inflammation and ROS suppression via inactivating TLR4?/NF-?κB and p38?/ERK1?/2 signaling pathways.
Biological Activity	ST1926 is an atypical retinoid th at is able to overcome resistance to ATRA. ST1926 appears to induce apoptosis by production of DNA double-strand breaks (DSB) and chromosomal lesions during the S phase of the cell cycle.', 'ST1926 is considered to be more apoptotic than CD437. It is much effective in mobilizing calcium than CD437. ST1926 repress toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88) signal pathway to disable the actions of nuclear factor-KB (NF-KB). It has the ability to repress inflammation response and ROS synthesis in lung epithelial cells in vitro.
target	RAR β

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid Preparation Products And Raw materials

Tag:(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid(496868-77-0) Related Product Information

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