Pexiganan manufacturers
- Pexiganan
-
- $80.00 / 1kg
-
2024-08-27
- CAS:172820-23-4
- Min. Order: 10kg
- Purity: 0.99
- Supply Ability: 20tons
|
| | Pexiganan Basic information |
| | Pexiganan Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: Slightly soluble,DMSO: Slightly soluble,Ethanol: 12 mg/ml,PBS (pH 7.2): 5 mg/ml | | form | A solid | | color | white to off-white | | Sequence | H-Gly-Ile-Gly-Lys-Phe-Leu-Lys-Lys-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Lys-Leu-Leu-Lys-Lys-NH2 |
| | Pexiganan Usage And Synthesis |
| Uses | Treatment of diabetic foot ulcer infections (antibacterial). | | Brand name | Cytolex (Abbott). | | Biological Activity | Pexiganan (MSI-78) is a 22-aa synthetic cationic antimicrobial peptide (AMP), an analog of magainin found in the African clawed frog (Xenopus laevis). Pexiganan is effective against both Gram-positive (staphylococci MIC ≤16 μg/mL, streptococci & methicillin-resistant S. aureus MIC 8-64 μg/mL, S. pyrogenes MIC 16-256 μg/mL) and Gram-negative aerobes (MIC 4-32 μg/mL, E. cloacae MCI 1-128 μg/mL, A. faecalis 4-64 μg/mL) by disrupting bacteria cell wall or membrane. |
| | Pexiganan Preparation Products And Raw materials |
|