| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:K-TMZ
CAS:2269482-26-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:K-TMZ
CAS:2269482-26-8
Purity:95% Package:1mg;5mg;10mg
|
| Company Name: |
Merck KGaA
|
| Tel: |
(+86) 21 2033 8288 |
| Email: |
sigmaname@qq.com |
| Products Intro: |
Product Name:K-TMZ
CAS:2269482-26-8
|
|
| Product Name: | K-TMZ | | Synonyms: | K-TMZ;Imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one, 8-acetyl-3-methyl-;8-acetyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one | | CAS: | 2269482-26-8 | | MF: | C7H7N5O2 | | MW: | 193.16 | | EINECS: | | | Product Categories: | | | Mol File: | 2269482-26-8.mol |  |
| | K-TMZ Chemical Properties |
| Boiling point | 390.5±34.0 °C(Predicted) | | density | 1.65±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF:10.0(Max Conc. mg/mL);51.77(Max Conc. mM)
DMSO:10.0(Max Conc. mg/mL);51.77(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);51.77(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);1.55(Max Conc. mM) | | pka | -1.67±0.20(Predicted) | | form | powder | | color | white to beige |
| | K-TMZ Usage And Synthesis |
| Description | K-TMZ is a DNA alkylating agent. It increases the concentration of O6-methylated deoxyguanosine in U87 glioblastoma multiforme (GBM) cells in a concentration-dependent manner. K-TMZ reduces cell viability of GBM cell lines lacking or expressing O6-methylguanine DNA methyltransferase (MGMT). | | target | A DNA alkylating agent. |
| | K-TMZ Preparation Products And Raw materials |
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