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DC Chemicals
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021-58447131 13564518121 |
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| Products Intro: |
Product Name:MRS1177
CAS:183721-13-3
Purity:98% HPLC Package:100mg，250mg，1g
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MRS1177 manufacturers
- MRS1177
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- $1980.00 / 50mg
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2024-10-24
- CAS:183721-13-3
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | MRS1177 Basic information |
| Product Name: | MRS1177 | | Synonyms: | MRS1177;MRS-1177,MRS1177;Benzamide, N-[9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-yl]- | | CAS: | 183721-13-3 | | MF: | C20H12ClN5O2 | | MW: | 389.79 | | EINECS: | | | Product Categories: | | | Mol File: | 183721-13-3.mol |  |
| | MRS1177 Chemical Properties |
| density | 1.53±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 6.69±0.46(Predicted) |
| | MRS1177 Usage And Synthesis |
| Description | MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM. MRS1177 (compound 2b) is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist[1]. The Ki value of MRS1177 (compound 55) with hA3AR is 0.3 nM[2]. | | References | [1]. Tafi A, et al. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97. [2]. Cheong SL, et al. Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists. Bioorg Med Chem Lett. 2011 May 15;21(10):2898-905. |
| | MRS1177 Preparation Products And Raw materials |
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