Company Name: |
BOC Sciences
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Tel: |
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Email: |
info@bocsci.com |
Products Intro: |
Product Name:LBX192 CAS:866772-52-3 Purity:98% Remarks:LBX192 is a Liver Targeted Glucokinase Activator. It can activate the GK enzyme in vitro at low nM concentrations and reduce glucose levels during an oral glucose tolerance test in normal as well as d
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:LBX192 CAS:866772-52-3 Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
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BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- manufacturers
- LBX192
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- $1980.00 / 50mg
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2024-10-24
- CAS:866772-52-3
- Min. Order:
- Purity:
- Supply Ability: 10g
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| BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- Basic information |
| BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- Chemical Properties |
density | 1.340±0.06 g/cm3(Predicted) | pka | 10.73±0.43(Predicted) |
| BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- Usage And Synthesis |
Description | LBX192, also known as NVP-LBX192, is a Liver Targeted Glucokinase Activator. LBX192 activated the GK enzyme in vitro at low nM concentrations and significantly reduced glucose levels during an oral glucose tolerance test in normal as well as diabetic mice. A GK activator has the promise of potentially affecting both the beta-cell of the pancreas, by improving glucose sensitive insulin secretion, as well as the liver, by reducing uncontrolled glucose output and restoring post prandial glucose uptake and storage as glycogen. |
| BenzeneacetaMide, α-(cyclopentylMethyl)-N-(5-Methoxythiazolo[5,4-b]pyridin-2-yl)-4-[(4-Methyl-1-piperazinyl)sulfonyl]-, (αR)- Preparation Products And Raw materials |
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