N2-(Isopropylphenoxyacetyl)guanosine manufacturers
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| | N2-(Isopropylphenoxyacetyl)guanosine Basic information |
| Product Name: | N2-(Isopropylphenoxyacetyl)guanosine | | Synonyms: | N2-(Isopropylphenoxyacetyl)guanosine;N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-(4-isopropylphenoxy)acetamide;Guanosine, N-[2-[4-(1-methylethyl)phenoxy]acetyl]- | | CAS: | 937205-20-4 | | MF: | C21H25N5O7 | | MW: | 459.45 | | EINECS: | | | Product Categories: | | | Mol File: | 937205-20-4.mol |  |
| | N2-(Isopropylphenoxyacetyl)guanosine Chemical Properties |
| density | 1.62±0.1 g/cm3(Predicted) | | pka | 7.19±0.20(Predicted) |
| | N2-(Isopropylphenoxyacetyl)guanosine Usage And Synthesis |
| Uses | N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. | | References | [1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100 |
| | N2-(Isopropylphenoxyacetyl)guanosine Preparation Products And Raw materials |
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