rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine

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Company Name:	TargetMol Chemicals Inc.
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Products Intro:	Product Name:E3 ligase Ligand 9 CAS:87304-15-2 Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Blocksynth Pharmaceutical Technology Co.,Ltd
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Products Intro:	Product Name:rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine CAS:87304-15-2 Purity:98% Package:25KG;USD

Company Name:	TargetMol Chemicals Inc.
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Products Intro:	Product Name:E3 ligase Ligand 9 CAS:87304-15-2 Package:100mg

Company Name:	Shanxi Tihondan Pharmaceutical Technology Co., Ltd
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Products Intro:	Product Name:E3 ligase Ligand 9 CAS:87304-15-2 Purity:95%+ Package:5g;10g;1kg;10kg

Company Name:	Jilin Chinese Academy of Sciences-yanshen Technology
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Products Intro:	Product Name:E3 Ligase ligand 9 CAS:87304-15-2 Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing

rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine manufacturers

rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine Basic information

Product Name:	rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine
Synonyms:	rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine;L-Leucine, N-[(2S,3R)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-1-oxo-4-phenylbutyl]-;(2S)-2-[(2S,3R)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
CAS:	87304-15-2
MF:	C21H32N2O6
MW:	408.49
EINECS:
Product Categories:
Mol File:	87304-15-2.mol

rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine Chemical Properties

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rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine Usage And Synthesis

Description	E3 Ligase ligand 9 targets ubiquitin-protein ligases in order to activate the E3 ubiquitin ligase. It can then treat metabolic disorders and psychiatric disorders.
Uses	E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
References	[1] Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575. DOI:10.1021/acs.jmedchem.7b00168

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