| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:~1 mg/mL, buffered aqueous glycerol solution, affinity isolated antibody
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-CALPAIN-94 (DOMAIN II, INSERT 1), LARGE SUBUNIT Basic information |
| | ANTI-CALPAIN-94 (DOMAIN II, INSERT 1), LARGE SUBUNIT Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous glycerol solution | | biological source | rabbit |
| | ANTI-CALPAIN-94 (DOMAIN II, INSERT 1), LARGE SUBUNIT Usage And Synthesis |
| Biological Activity | Calpain is a heterodimer consisting of a larger and a smaller subunit. It is a major intracellular protease. Calpains are a family of calcium-dependent thiol-proteases, which are involved in many physiological processes and pathological conditions. These are calcium-activated non-lysosomal thiolproteases. m- and μ-calpain are ubiquitously expressed and are countered by the endogenous calpain inhibitor calpastatin. Calpains are present in all mammalian tissues and are involved in a variety of processes including cell proliferation, differentiation, vesicle secretion and others. It is also likely to be involved in processing of numerous enzymes and cytoskeletal components by linking their activity to a variety of intracellular events. |
| | ANTI-CALPAIN-94 (DOMAIN II, INSERT 1), LARGE SUBUNIT Preparation Products And Raw materials |
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