N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester)

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Company Name:	Jilin Chinese Academy of Sciences-yanshen Technology
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Products Intro:	Product Name:N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) CAS:2112732-01-9 Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing

Company Name:	Xian confluore Biological Technology Co., Ltd.
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Products Intro:	Product Name:N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methylester) CAS:2112732-01-9 Purity:>95.00% Package:250mg

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Products Intro:	Product Name:N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) CAS:2112732-01-9 Purity:98% Package:$961.9/100mg;$1951.9/250mg;$2941.9/500mg;Bulk package Remarks:98%

Company Name:	Xi'an Confluore Biological Technology Co., Ltd.
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Products Intro:	Product Name:N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methylester) CAS:2112732-01-9 Purity:95% HPLC Package:10MG;25MG;50MG;100MG;1G;5G

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) manufacturers

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) Basic information

Product Name:	N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester)
Synonyms:	N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester);4,11,14,17,20-Pentaoxa-7-azatricos-22-ynoic acid, 7-[2-(3-methoxy-3-oxopropoxy)ethyl]-8-oxo-, methyl ester
CAS:	2112732-01-9
MF:	C24H41NO11
MW:	519.58
EINECS:
Product Categories:
Mol File:	2112732-01-9.mol

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) Chemical Properties

Safety Information

MSDS Information

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) Usage And Synthesis

Description	N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a crosslinker that can react with azide compounds or biomolecules via copper catalyzed Click Chemistry to form a stable triazole linkage. The methyl ester groups can be hydrolyzed, reduced, or substituted under different conditions.
Uses	N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50	PEGs
References	[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) Preparation Products And Raw materials

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