(Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone
| 中文名稱 | (Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone |
|---|---|
| 中文同義詞 | (Z - )- 4-溴-5-(溴亞甲基)-2(5H)- 呋喃酮;呋喃酮 C-30;(?Z?-)-4-溴-5-(溴乙烯)-2 (5?H?)-呋喃酮 |
| 英文名稱 | (Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone |
| 英文同義詞 | (Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone;(Z-)-4-BROMO-5-(BROMOMETHYLENE)-2(5H;2(5H)-Furanone, 4-bromo-5-(bromomethylene)-, (5Z)-;Furanone C-30;(5Z)-4-Bromo-5-(bromomethylene)-2(5H)-furanone;(Z-)-4-Bromo-5-(bromomethylene)-2(5H)-furanone >=97.0% (GC);(5Z)-4-bromo-5-(bromomethylidene)-2，5-dihydrofuran-2-one;(Z)-4-Bromo-5-(brommethylen)-2(5H)-furanone |
| CAS號(hào) | 247167-54-0 |
| 分子式 | C5H2Br2O2 |
| 分子量 | 253.88 |
| EINECS號(hào) | |
| 相關(guān)類別 | |
| Mol文件 | 247167-54-0.mol |
| 結(jié)構(gòu)式 |  |
(Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone 性質(zhì)
| 熔點(diǎn) | 97-99 °C |
|---|---|
| 沸點(diǎn) | 205.9±40.0 °C(Predicted) |
| 密度 | 2.650±0.06 g/cm3(Predicted) |
| 儲(chǔ)存條件 | -20°C |
| 溶解度 | 溶于二甲基亞砜 |
| 形態(tài) | 固體 |
| 顏色 | 白色至米白色 |
| BRN | 120928 |
Furanone C-30 是一種細(xì)菌 (bacterial) 群體感應(yīng)抑制劑。Furanone C-30 可有效抑制細(xì)菌 (如 S. mutans 及其 luxS 突變株) 生物膜形成。
Bacterial biofilm
The difference in the OD590 values is statistically significant at concentrations of 2.0 μg/mL and 4.0 μg/mL compared with the control group. Furanone C-30 (2.0 μg/mL and 4.0 μg/mL) can inhibit biofilm formation by S. mutans and its luxS mutant strain, although it does not affect the bacterial growth rate itself.
Cell Viability Assay
| Cell Line: | Streptococcus mutans UA159 and its luxS mutant strain |
| Concentration: | 0.0, 2.0 and 4.0 μg/mL |
| Incubation Time: | 24 hours |
| Result: | When 2.0 μg/mL was added, the OD590 values for S. mutans and its luxS mutant strain decreased by 42.7% and 40.8%, respectively. When the concentration was increased to 4.0 μg/mL, a decrease of 61.5% and 60.3%, respectively. |
安全信息
| WGK Germany | 3 |
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