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61825-94-3 Basic information More..
Product Name:Oxaliplatin
Synonyms:[SP-4-2-(1R-TRANS)]-(1,2-CYCLOHEXANEDIAMINE-N,N')[ETHANEDIOATA(2-)-O,O']PLATINUM;OXALIPLATIN;trans-l-diaminocyclohexane oxalatoplatinum;(1,2-cyclohexanediamine-n,n’)(ethanedioato(2-)-o,o’)-platinu(sp-4-2-(1r-tr;oxalato(1r,2r-cyclohexanediammine)platinum(ii);oxalatoplatin;[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N,)[ethanedioato(2-)-O,O’Jplatinum;NSC-266046:Elocatin
CAS:61825-94-3
MF:C8H12N2O4Pt
MW:395.28
EINECS:621-248-1
Mol File:61825-94-3.mol
61825-94-3

Use

Oxaliplatin is a platinum-based antineoplastic agent that functions by forming DNA adducts specifically in cancer cells, preventing DNA replication and transcription which leads to cell death. Oxaliplatin has cytotoxic effects in a broad range of cell lines, including colon, ovarian, and lung cancer, with IC50 values ranging from 0.5-240, 0.12-19.8, and 2.6-6.1 μM, respectively. Through its general cytotoxic effects, oxaliplatin has anti-tumor activity against advanced colorectal cancer and is typically administered with fluorouracil and leucovorin in a combination known as FOLFOX.

Oxaliplatin manufacturers

  • Oxaliplatin
  • US $0.00 / KG
  • 2025-01-26
  • CAS:61825-94-3
  • Min. Order: 2KG
  • Purity: EP7.2
  • Supply Ability: 20tons
  • Oxaliplatin
  • US $200.00-95.00 / kg
  • 2025-01-24
  • CAS:61825-94-3
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 20ton
  • Oxaliplatin
  • US $0.00-0.00 / g
  • 2025-01-21
  • CAS:61825-94-3
  • Min. Order: 10g
  • Purity: 99% HPLC
  • Supply Ability: 1000kg
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