R788(Fostamatinib disodium)
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2物価
選択條件:
ブランド
- 富士フイルム和光純薬株式會社(wako)
パッケージ
- 1mg
- 5mg
- 生産者富士フイルム和光純薬株式會社(wako)
- 製品番號W01BVI1936-5
- 製品説明
- 英語製品説明Fostamatinib Disodium
- 包裝単位5mg
- 価格¥102700
- 更新しました2020-09-21
- 購入
- 生産者富士フイルム和光純薬株式會社(wako)
- 製品番號W01BVI1936-1
- 製品説明
- 英語製品説明Fostamatinib Disodium
- 包裝単位1mg
- 価格¥26000
- 更新しました2020-09-21
- 購入
生産者 | 製品番號 | 製品説明 | 包裝単位 | 価格 | 更新時間 | 購入 |
---|---|---|---|---|---|---|
富士フイルム和光純薬株式會社(wako) | W01BVI1936-5 | Fostamatinib Disodium |
5mg | ¥102700 | 2020-09-21 | 購入 |
富士フイルム和光純薬株式會社(wako) | W01BVI1936-1 | Fostamatinib Disodium |
1mg | ¥26000 | 2020-09-21 | 購入 |
プロパティ
融點(diǎn) :>191°C (dec.)
貯蔵溫度 :Store at -20°C
溶解性 :DMSO (Slightly), Methanol (Slightly)
外見 :Solid
色 :Off-White
安定性: :Hygroscopic
貯蔵溫度 :Store at -20°C
溶解性 :DMSO (Slightly), Methanol (Slightly)
外見 :Solid
色 :Off-White
安定性: :Hygroscopic
安全情報
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説明
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that upon phosphorylation binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet function and inflammation. R788 is a prodrug of R406 , an inhibitor of Syk (Ki = 30 nM). R788 conversion to the biologically active R406 is catalyzed by the action of alkaline phosphatases present on the apical brush-border of the membranes of intestinal enterocytes. It produces anti-inflammatory and immunomodulating effects by inhibiting Syk-mediated IgG Fcγ receptor signaling, which prevents activation of mast cells, macrophages, and B cells, as well as related inflammatory responses. R788 has undergone clinical evaluation for efficacy in the treatment of rheumatoid arthritis.関連商品価格
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供給者とメーカー
ATK CHEMICAL COMPANY LIMITED
career henan chemical co
Biochempartner
Shandong chuangyingchemical Co., Ltd.
TargetMol Chemicals Inc.
Hubei Ipure Biology Co., Ltd
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
changzhou huayang technology co., ltd