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ChemicalBook >> CAS DataBase List >> Z-VAD-FMK

Z-VAD-FMK

Z-VAD-FMK price.
  • $50 - $1950
  • Product name: Z-VAD-FMK
  • CAS: 187389-52-2
  • MF: C22H30FN3O7
  • MW: 467.49
  • EINECS:
  • MDL Number:MFCD03452883
  • Synonyms:Z-VADC(OME)-FMK;methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-phenylmethoxycarbonylamino-butanoyl]amino]propanoyl]amino]-4-oxo-pentanoate;N-BENZYLOXYCARBONYL-VAL-ALA-ASP FLUOROMETHYL KETONE;Z-VAD-FLUOROMETHYLKETONE;Z-VAD-FMK;Z-VAD-FMK, METHYL ESTER;Z-VAD(OME)-FLUOROMETHYLKETONE;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-
33 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Ark Pharm
  • Cayman Chemical
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 100μg
  • 50mg
  • 250mg
  • 2mg
  • 1
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CP3-0002-M001
  • Product descriptionZ-VAD-FMK(Cellpermeable) ≥95%(HPLC)
  • Packaging1mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2822AH
  • Product descriptionZ-VAD(OMe)-FMK
  • Packaging100mg
  • Price$1950
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA354225
  • Product descriptionZ-VAD(OMe)-FMK 98+%
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA354225
  • Product descriptionZ-VAD(OMe)-FMK 98+%
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA354225
  • Product descriptionZ-VAD(OMe)-FMK 98+%
  • Packaging10mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA354225
  • Product descriptionZ-VAD(OMe)-FMK 98+%
  • Packaging25mg
  • Price$435
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000247
  • Product descriptionZ-VAD-FMK METHYL ESTER 95.00%
  • Packaging5MG
  • Price$504.66
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1902
  • Product descriptionZ-VAD-FMK
  • Packaging1mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1902
  • Product descriptionZ-VAD-FMK
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1902
  • Product descriptionZ-VAD-FMK
  • Packaging10mM(in 1mL DMSO)
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1902
  • Product descriptionZ-VAD-FMK
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1902
  • Product descriptionZ-VAD-FMK
  • Packaging25mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS031017
  • Product descriptionZ-VAD(OMe)-FMK ≥98%
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS031017
  • Product descriptionZ-VAD(OMe)-FMK ≥98%
  • Packaging5mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS031017
  • Product descriptionZ-VAD(OMe)-FMK ≥98%
  • Packaging10mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60020
  • Product descriptionZ-VAD-FMK
  • Packaging5mg
  • Price$288
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CP3-0002-M001 Z-VAD-FMK(Cellpermeable) ≥95%(HPLC) 1mg $145 2021-12-16 Buy
AK Scientific 2822AH Z-VAD(OMe)-FMK 100mg $1950 2021-12-16 Buy
Ambeed A354225 Z-VAD(OMe)-FMK 98+% 1mg $50 2021-12-16 Buy
Ambeed A354225 Z-VAD(OMe)-FMK 98+% 5mg $150 2021-12-16 Buy
Ambeed A354225 Z-VAD(OMe)-FMK 98+% 10mg $240 2021-12-16 Buy
Ambeed A354225 Z-VAD(OMe)-FMK 98+% 25mg $435 2021-12-16 Buy
American Custom Chemicals Corporation INB0000247 Z-VAD-FMK METHYL ESTER 95.00% 5MG $504.66 2021-12-16 Buy
ApexBio Technology A1902 Z-VAD-FMK 1mg $55 2021-12-16 Buy
ApexBio Technology A1902 Z-VAD-FMK 5mg $150 2021-12-16 Buy
ApexBio Technology A1902 Z-VAD-FMK 10mM(in 1mL DMSO) $150 2021-12-16 Buy
ApexBio Technology A1902 Z-VAD-FMK 10mg $250 2021-12-16 Buy
ApexBio Technology A1902 Z-VAD-FMK 25mg $400 2021-12-16 Buy
Arctom AS031017 Z-VAD(OMe)-FMK ≥98% 1mg $50 2021-12-16 Buy
Arctom AS031017 Z-VAD(OMe)-FMK ≥98% 5mg $148 2021-12-16 Buy
Arctom AS031017 Z-VAD(OMe)-FMK ≥98% 10mg $238 2021-12-16 Buy
Arctom CFN60020 Z-VAD-FMK 5mg $288 2021-12-16 Buy

Properties

Melting point :>190°C (dec.)
Boiling point :732.4±60.0 °C(Predicted)
Density :1.214±0.06 g/cm3 (20 ºC 760 Torr)
Flash point :396.7℃
storage temp. :-20°C
solubility :DMSO: 20 mg/mL
form :powder
pka :11.05±0.46(Predicted)
color :white
biological source :synthetic
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey :MIFGOLAMNLSLGH-QOKNQOGYSA-N
SMILES :C(N)(=O)[C@H](C)N(C(=O)[C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)[C@@H](CC(OC)=O)C(=O)CF
CAS DataBase Reference :187389-52-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases. Through this action, it inhibits cleavage of poly(ADP-ribose) polymerase, preventing apoptosis when used at 10-50 μM. It also blocks caspase-mediated apoptosis in vivo. Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes.

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