Ingenol mebutate
![]() |
- $74 - $2150
- Product name: Ingenol mebutate
- CAS: 75567-37-2
- MF: C25H34O6
- MW: 430.53
- EINECS:
- MDL Number:MFCD22683801
- Synonyms:Ingenol-3-O-angelate;Picato;(1aR,2S,5R,5aS,6S,8aS,9R,10aR)-5,5a-Dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a- methanocyclopenta(a)cyclopropa(e)cyclodecen-6-yl (2Z)-2-methylbut-2-enoate;Ingenol mebutate;Ingenol Mebutate, >98%;Ingenol 3-mebutate;Ingenol-3-O-angelate 75567-37-2;PEP005; INGENOL MEBUTATE; I3A
25 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 500μg
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 20mg
- 25mg
- 100mg
- 250mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0012-M005
- Product descriptionIngenol-3-angelate ≥97%(HPLC)
- Packaging5mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3737AH
- Product descriptionIngenol3-angelate
- Packaging10mg
- Price$977
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60601
- Product descriptionIngenol 3-angelate, 98%
- Packaging1mg
- Price$306
- Updated2023-06-20
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005276
- Product descriptionINGENOL 3-ANGELATE 95.00%
- Packaging1MG
- Price$258.3
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY232574
- Product descriptionIngenol-3-angelate;Ingenol?mebutate
- Packaging10mg
- Price$1423.64
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3018
- Product descriptionIngenol-3-angelate
- Packaging2mg
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3018
- Product descriptionIngenol-3-angelate
- Packaging5mg
- Price$149
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3018
- Product descriptionIngenol-3-angelate
- Packaging10mg
- Price$249
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3018
- Product descriptionIngenol-3-angelate
- Packaging25mg
- Price$429
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3018
- Product descriptionIngenol-3-angelate
- Packaging100mg
- Price$1150
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3018
- Product descriptionIngenol-3-angelate
- Packaging250mg
- Price$2150
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16207
- Product descriptionIngenol-3-angelate ≥95%
- Packaging500μg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16207
- Product descriptionIngenol-3-angelate ≥95%
- Packaging1mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16207
- Product descriptionIngenol-3-angelate ≥95%
- Packaging5mg
- Price$553
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16207
- Product descriptionIngenol-3-angelate ≥95%
- Packaging10mg
- Price$790
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-2971
- Product descriptionIngenolMebutate 99.07%
- Packaging1mg
- Price$74
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CN2-0012-M005 | Ingenol-3-angelate ≥97%(HPLC) | 5mg | $420 | 2021-12-16 | Buy |
AK Scientific | 3737AH | Ingenol3-angelate | 10mg | $977 | 2021-12-16 | Buy |
Alfa Aesar | J60601 | Ingenol 3-angelate, 98% | 1mg | $306 | 2023-06-20 | Buy |
American Custom Chemicals Corporation | API0005276 | INGENOL 3-ANGELATE 95.00% | 1MG | $258.3 | 2021-12-16 | Buy |
Arctom | SY232574 | Ingenol-3-angelate;Ingenol?mebutate | 10mg | $1423.64 | 2021-12-16 | Buy |
AvaChem | 3018 | Ingenol-3-angelate | 2mg | $89 | 2021-12-16 | Buy |
AvaChem | 3018 | Ingenol-3-angelate | 5mg | $149 | 2021-12-16 | Buy |
AvaChem | 3018 | Ingenol-3-angelate | 10mg | $249 | 2021-12-16 | Buy |
AvaChem | 3018 | Ingenol-3-angelate | 25mg | $429 | 2021-12-16 | Buy |
AvaChem | 3018 | Ingenol-3-angelate | 100mg | $1150 | 2021-12-16 | Buy |
AvaChem | 3018 | Ingenol-3-angelate | 250mg | $2150 | 2021-12-16 | Buy |
Cayman Chemical | 16207 | Ingenol-3-angelate ≥95% | 500μg | $81 | 2024-03-01 | Buy |
Cayman Chemical | 16207 | Ingenol-3-angelate ≥95% | 1mg | $152 | 2024-03-01 | Buy |
Cayman Chemical | 16207 | Ingenol-3-angelate ≥95% | 5mg | $553 | 2024-03-01 | Buy |
Cayman Chemical | 16207 | Ingenol-3-angelate ≥95% | 10mg | $790 | 2024-03-01 | Buy |
ChemScene | CS-2971 | IngenolMebutate 99.07% | 1mg | $74 | 2021-12-16 | Buy |
Properties
Boiling point :576.9±50.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :11.52±0.70(Predicted)
color :white to beige
biological source :semisynthetic
Water Solubility :Soluble in 100% ethanol, DMSO, dichloromethane, and methanol. Insoluble in water.
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :VDJHFHXMUKFKET-WDUFCVPESA-N
SMILES :C(O[C@@H]1[C@@]2(O)[C@H](O)C(CO)=C[C@]3([H])C(=O)[C@]2(C=C1C)[C@H](C)C[C@@]1([H])C(C)(C)[C@]13[H])(=O)/C(/C)=C\C
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :11.52±0.70(Predicted)
color :white to beige
biological source :semisynthetic
Water Solubility :Soluble in 100% ethanol, DMSO, dichloromethane, and methanol. Insoluble in water.
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :VDJHFHXMUKFKET-WDUFCVPESA-N
SMILES :C(O[C@@H]1[C@@]2(O)[C@H](O)C(CO)=C[C@]3([H])C(=O)[C@]2(C=C1C)[C@H](C)C[C@@]1([H])C(C)(C)[C@]13[H])(=O)/C(/C)=C\C
Safety Information
Symbol(GHS): |
![]() ![]() |
||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Danger | ||||||||||||||||||||||||||||||||||||||||
Hazard statements: |
|
||||||||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Ingenol-3-angelate is a hydrophobic diterpene ester that can be isolated from the euphorb E. peplus. It rapidly induces cell death in proliferating keratinocytes through plasma membrane and mitochondrial disruption, although it can also initiate apoptosis in some cancer cell lines (LD90 = ~190 μM). Secondarily, ingenol-3-angelate causes inflammation due, at least in part, to activation of PKC, leading to antibody-dependent cellular cytotoxicity. These actions have relevance in diminishing actinic keratosis and, possibly, other cancers of the skin.More related product prices
Columbianadin 74050-97-8 Imiquimod Betulinic acid INGENOL Lead Vorinostat Imatinib mesylate KetoconazoleRelated product price
- Columbianadin
$29-1320 - 74050-97-8
$220-1250 - Imiquimod
$6-990
Suppliers and manufacturers
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Hubei Jusheng Technology Co.,Ltd.
Chongqing Chemdad Co., Ltd
Wuhan ChemNorm Biotech Co.,Ltd.