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4-[(3-??????)??]???????

4-[(3-??????)??]???????
4-[(3-??????)??]??????? ??? ???
?? ??:
405-85-6
???:
4-[(3-??????)??]???????
???(??):
4-[(3-??????)??]???????
???:
4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID
???(??):
NW-1689;TIMTEC-BB SBB010215;Safinamide Impueity C;Safinamide Impurity E;ASINEX-REAG BAS 13355063;Safinamide Metabolite NW 1689;Safinamide Benzoic Acid Impurity;4-[(3-FLUOROBENZYL)OXY]BENZOIC ACID;4-[(3-fluorophenyl)methoxy]benzoate;4-[(3-fluorophenyl)methoxy]benzoic acid
CBNumber:
CB4366782
???:
C14H11FO3
??? ??:
246.23
MOL ??:
405-85-6.mol

4-[(3-??????)??]??????? ??

???
194-196°C
?? ?
393.4±22.0 °C(Predicted)
??
1.289±0.06 g/cm3(Predicted)
?? ?? (pKa)
4.40±0.10(Predicted)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ?? IRRITANT
HS ?? 2918999090
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321 (…) ??? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P362 ??? ??? ?? ?? ?? ?????

4-[(3-??????)??]??????? C??? ??, ??, ??

??

4-[(3-Fluorobenzyl)oxy]benzoic acid is a metabolite of Safinamide. Safinamide is a potent and selective MAO-B inhibitor, and is used as an add-on treatment to treat Parkinson’s disease.

4-[(3-??????)??]??????? ?? ?? ? ???

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4-[(3-??????)??]??????? ?? ??

???( 49)?? ??
??? ?? ??? ?? ?? ? ??
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