抗NR2C2抗體 ウサギ宿主抗體 化學特性,用途語,生産方法
使用
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project
(www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these
protocols and other useful information about Prestige Antibodies and the HPA, visit .
一般的な説明
NR2C2 (nuclear receptor subfamily 2, group C, member 2) is a protein encoded by the NR2C2 gene in humans and is mapped to chromosome to 3p25. It is a novel member of the nuclear hormone receptor family. It is localized to the hippocampus and the cerebellum in the granule cells. It may also have some role in the transcriptional regulation of neurons. It is found to be highly conserved in rat and human.
Biochem/physiol Actions
Testicular nuclear receptor 4 (TR4) confers protection against oxidative stress and DNA damage, and may be involved in aging. It might have potential as a biomarker for prostate cancer (PCa) metastasis. Its interaction with keto-Mycolic acid (MA) is unique in that a host nuclear receptor binding with a bacterial lipid. It is involved in the final stages of differentiation of human erythroid cells, where it controls the basic and essential biological processes. It activates NF-κB in a genotoxic-stress mediated manner. Inactivation of this gene enhances apoptosis of neuroblastoma cells during chemotherapy.
抗NR2C2抗體 ウサギ宿主抗體 上流と下流の製品情報
原材料
準備製品