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アンジオテンシン変換酵素 ウサギ肺由來

アンジオテンシン変換酵素 ウサギ肺由來 化學(xué)構(gòu)造式
9015-82-1
CAS番號.
9015-82-1
化學(xué)名:
アンジオテンシン変換酵素 ウサギ肺由來
別名:
アンジオテンシン変換酵素 ウサギ肺由來;アンジオテンシン変換酵素 ブタ腎臓由來
英語名:
EC 3.4.15.1
英語別名:
ACE;ANGIOTENSIN CONVERTING ENZYME;ACE (HUMAN);EC 3.4.15.1;ACE (enzyme);Carboxycathepsin;Carboxypeptidase Zace2;PEPTIDYLDIPEPTIDE HYDROLASE;ACE, Peptidyl-dipeptidaseA;Angiotens Converting Enzyme
CBNumber:
CB3358160
化學(xué)式:
C2H5NO
分子量:
59.0672
MOL File:
9015-82-1.mol
MSDS File:
SDS

アンジオテンシン変換酵素 ウサギ肺由來 物理性質(zhì)

貯蔵溫度 :
-20°C
外見 :
凍結(jié)乾燥粉末
色:
Off-white to light yellow
Specific Activity:
≥2.0units/mg protein (modified Warburg-Christian)
安全性情報
  • リスクと安全性に関する聲明
  • 危険有害性情報のコード(GHS)
WGK Germany  3
10-21
絵表示(GHS) GHS hazard pictograms
注意喚起語 危険
危険有害性情報
コード 危険有害性情報 危険有害性クラス 區(qū)分 注意喚起語 シンボル P コード
H334 吸入するとアレルギー、喘息または、呼吸困難 を起こすおそれ 感作性、呼吸器 1 危険 GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
注意書き
P261 粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
P284 呼吸用保護(hù)具を著用すること。
P501 內(nèi)容物/容器を...に廃棄すること。

アンジオテンシン変換酵素 ウサギ肺由來 価格 もっと(40)

メーカー 製品番號 製品説明 CAS番號 包裝 価格 更新時間 購入
Sigma-Aldrich Japan Z568910 Aceプレッシャーチューブ bushing type, Back seal, capacity 140?mL, L × O.D. 20.3?cm × 38.1?mm
bushing type, Back seal, capacity 140?mL, L × O.D. 20.3?cm × 38.1?mm
9015-82-1 1EA ¥25600 2024-03-01 購入
Sigma-Aldrich Japan Z568902 Aceプレッシャーチューブ bushing type, Back seal, capacity 120?mL, L × O.D. 17.8?cm × 38.1?mm
bushing type, Back seal, capacity 120?mL, L × O.D. 17.8?cm × 38.1?mm
9015-82-1 1EA ¥25400 2024-03-01 購入
Sigma-Aldrich Japan Z568880 Aceプレッシャーチューブ bushing type, Back seal, capacity 185?mL, L × O.D. 30.5?cm × 38.1?mm
bushing type, Back seal, capacity 185?mL, L × O.D. 30.5?cm × 38.1?mm
9015-82-1 1EA ¥23000 2024-03-01 購入
Sigma-Aldrich Japan Z568872 Aceプレッシャーチューブ bushing type, Back seal, capacity 60?mL, L × O.D. 30.5?cm × 25.4?mm
bushing type, Back seal, capacity 60?mL, L × O.D. 30.5?cm × 25.4?mm
9015-82-1 1EA ¥17700 2024-03-01 購入
Sigma-Aldrich Japan Z568848 Aceプレッシャーチューブ bushing type, Front seal, capacity 210?mL, L × O.D. 30.5?cm × 38.1?mm
bushing type, Front seal, capacity 210?mL, L × O.D. 30.5?cm × 38.1?mm
9015-82-1 1EA ¥28000 2024-03-01 購入

アンジオテンシン変換酵素 ウサギ肺由來 化學(xué)特性,用途語,生産方法

使用

Angiotensin converting enzyme from rabbit lung has been used:
  • for measuring inhibitory effect of egg white protein hydrolysates on ACE activity by high performance liquid chromatography (HPLC)
  • to measure the ACE inhibition by litchi pericarp and cooked chicken breast using hippuryl-L-histidyl-L-leucine (HHL) as substrate by reverse phase-HPLC (RP-HPLC)3 and HPLC respectively
  • in releasing GPI anchored protein in vitro in few cell lines like HeLa, HEK293 and in vivo in mice sperm.

一般的な説明

The angiotensin-converting enzyme (ACE) is a dipeptidyl-carboxypeptidase which exists in somatic and testicular isoforms with zinc binding motif HEXXH in their active site. ACE regulates blood pressure through renin-angiotensin system. ACE elevates blood pressure by converting angiotensin I to a key vasoconstrictor angiotensin II and inhibiting a potent vasodilator bradykinin. Inhibition of ACE is a targeted therapeutic strategy for high blood pressure. Several ACE synthetic inhibitory peptides available for clinical use include captopril, enalapril and lisinopril. Currently, developing inhibitory peptides from natural food sources, or phenolic compounds from plant sources to inhibit ACE is underway. ACE plays a critical role in fertilization by releasing the proteins anchored to glycosylphosphatidylinositol (GPI) in sperm membrane.

純化方法

Purify ACE by fractionation on DEAE-cellulose, Ca phosphate gel chromatography, elution from Sephadex G-200 and lectin affinity chromatography. The MW varied with glycosidation and is higher by gel filtration. It contains one atom of Zn/mol and has Km values for hydrolysis of hippurylhistidinylleucine and angiotensin I of 2.3 and 0.07 mM, and turnover of 15,430 and 792 mol/min/mol at 37o, respectively. The activity is inhibited by EDTA and increased amounts of Ca ions but required Ca ions. [Das & Soffer J Biol Chem 250 6762 1975, Reviewed by Ehlers & Riordan Biochemistry 28 5311 1989.]

アンジオテンシン変換酵素 ウサギ肺由來 上流と下流の製品情報

原材料

準(zhǔn)備製品


アンジオテンシン変換酵素 ウサギ肺由來 生産企業(yè)

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9015-82-1(アンジオテンシン変換酵素 ウサギ肺由來)キーワード:


  • 9015-82-1
  • PEPTIDYLDIPEPTIDE HYDROLASE
  • ANGIOTENSIN CONVERTING ENZYME FROMRABBIT LUNG
  • ANGIOTENSIN-CONVERTIN-GAMMA-ENZYME
  • ANGIOTENSIN CONVERTING ENZYME (HUMAN)
  • ACE (HUMAN)
  • ACE (enzyme)
  • Angiotensin converting enzyme 1
  • Angiotensin I-converting enzyme
  • Angiotensin-1 converting enzyme
  • Angiotensin-converting enzyme I
  • Angiotension-converting enzyme
  • Carboxycathepsin
  • Carboxypeptidase Zace2
  • Dipeptidyl carboxypeptidase A
  • Dipeptidyl carboxypeptidase I
  • Dipeptidyl serine carboxypeptidase
  • ANGIOTENSIN CONVERTING ENZYME FROMPORCIN E KIDNEY
  • ANGIOTENSIN-CONVERTING-ENZYME F. RABBIT LUNG, ~3 U/MG
  • ACE, Peptidyl-dipeptidaseA, Peptidyldipeptide Hydrolase
  • ACE, Peptidyl-dipeptidaseA
  • Angiotensin Converting Enzyme from porcine kidney,ACE, Peptidyl-dipeptidaseA
  • Angiotensin Converting Enzyme from rabbit lung,ACE, Peptidyl-dipeptidaseA, Peptidyldipeptide Hydrolase
  • Carboxypeptidase,dipeptidyl, A
  • EC 3.4.15.1
  • Native Rabbit Angiotensin Converting Enzyme
  • Native Rat Angiotensin Converting Enzyme
  • Native Porcine Angiotensin Converting Enzyme
  • Recombinant Human CD143/ACE Protein, His Tag
  • ANGIOTENSIN CONVERTING ENZYME
  • ACE
  • アンジオテンシン変換酵素 ウサギ肺由來
  • アンジオテンシン変換酵素 ブタ腎臓由來
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