2,3-DCPE 化學(xué)特性,用途語(yǔ),生産方法
説明
2,3-
DCPE is a proapoptotic compound with selectivity for cancer cells
versus normal human cells. It induces apoptosis
in vitro in various cancer cell lines (IC
50s = 0.89-
2.69 μM) more effectively than in normal human fibroblasts (IC
50 = 12.6 μM). 2,3-
DCPE down-
regulates Bcl-
xL, however forced overexpression of Bcl-
xL is sufficient to block 2,3-
DCPE apoptosis induction. 2,3-
DCPE can induce S-
phase arrest, upregulate p21, and activate ERK.
使用
2,3-DCPE is a compound that induces both upregulation and S-phase arrest in p21. Used as an anti-cancer treatment as it induces apoptosis.
2,3-DCPE 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品