ChemicalBook >> CAS DataBase List >>Fatostatin A
Fatostatin A
- CAS No.
- 125256-00-0
- Chemical Name:
- Fatostatin A
- Synonyms
- 125B11;2-(2-propylpyridin-4-yl)-4-(p-tolyl)thiazole;Pyridine, 4-[4-(4-methylphenyl)-2-thiazolyl]-2-propyl-;4-(4-methylphenyl)-2-(2-propylpyridin-4-yl)-1,3-thiazole;mice,125B11,prostate,cancer,Fatty Acid Synthase (FASN),gene,human,insulin-induced,Fatostatin,ob/ob,inhibit,expression,Golgi,Inhibitor,adipogenesis,SREBP-mediated
- CBNumber:
- CB92627880
- Molecular Formula:
- C18H18N2S
- Molecular Weight:
- 294.41
- MDL Number:
- MFCD02376000
- MOL File:
- 125256-00-0.mol
- MSDS File:
- SDS
Last updated:2024-11-19 15:53:33
| Boiling point | 474.3±55.0 °C(Predicted) |
|---|---|
| Density | 1.125±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Soluble in DMSO (up to 25 mg/ml). |
| form | solid |
| pka | 3.46±0.10(Predicted) |
| color | Yellow |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H413-H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
Fatostatin A price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-5810 | Fatostatin | 125256-00-0 | 5mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-5810 | Fatostatin | 125256-00-0 | 10mg | $78 | 2021-12-16 | Buy |
| ChemScene | CS-5810 | Fatostatin | 125256-00-0 | 50mg | $245 | 2021-12-16 | Buy |
| ChemScene | CS-5810 | Fatostatin | 125256-00-0 | 100mg | $420 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0013907 | FATOSTATIN A 95.00% | 125256-00-0 | 5MG | $498.17 | 2021-12-16 | Buy |
Fatostatin A Chemical Properties,Uses,Production
Description
Fatostatin (125256-00-0) blocks adipogenesis by inhibiting the activation of SREBP. Inhibits the ER-Golgi translocation of SREBPs via binding to their escort protein (SCAP). Fatostatin prevents increases in body weight, blood glucose, and hepatic fat accumulation in obese ob/ob mice.1?Inhibits high glucose-induced TGF-β in mesangial cells.2?Cell permeable.
Uses
Fatostatin A is Cell permeable inhibitor of SREBP activation.
Definition
ChEBI: 4-(4-methylphenyl)-2-(2-propyl-4-pyridinyl)thiazole is a member of thiazoles.
References
1) Kamisuki et al. (2009), A small molecule that blocks fat synthesis by inhibiting the activation of SREBP; Chem. Biol., 16 882 2) Uttarwar et al. (2012), SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells; Am. J. Physiol. Renal Physiol., 302 F329
Fatostatin A Preparation Products And Raw materials
Raw materials
Preparation Products
Fatostatin A Suppliers
Global( 49)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32956 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30236 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | chenyj@titansci.com | China | 14103 | 59 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9891 | 58 |
View Lastest Price from Fatostatin A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Fatostatin
125256-00-0
|
US $30.00-67.00 / mg | 99.94% | 10g | TargetMol Chemicals Inc. |
-
- Fatostatin
125256-00-0
- US $30.00-67.00 / mg
- 99.94%
- TargetMol Chemicals Inc.
125256-00-0(Fatostatin A)Related Search:
4-(4-methylphenyl)-2-(2-propylpyridin-4-yl)-1,3-thiazole
125B11
Pyridine, 4-[4-(4-methylphenyl)-2-thiazolyl]-2-propyl-
2-(2-propylpyridin-4-yl)-4-(p-tolyl)thiazole
mice,125B11,prostate,cancer,Fatty Acid Synthase (FASN),gene,human,insulin-induced,Fatostatin,ob/ob,inhibit,expression,Golgi,Inhibitor,adipogenesis,SREBP-mediated
125256-00-0