ChemicalBook >> CAS DataBase List >>Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]-

Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]-

Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]- structure

CAS No.: 1476847-58-1

Chemical Name:: Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]-

Synonyms: VU0652925;VU-0652925;VU 0652925;Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]-

CBNumber:: CB89827912

Molecular Formula:: C24H18N4O4S2

Molecular Weight:: 490.55

MDL Number:

MOL File:: 1476847-58-1.mol

Last updated:2025-05-09 19:07:32

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Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]- Properties

Density	1.50±0.1 g/cm3(Predicted)
pka	0.55±0.10(Predicted)

Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]- Chemical Properties,Uses,Production

Description

VU0652925 is a PAR4 antagonist. VU0652925 had a PAC1 IC50 of 43.0 pM (-pIC50±SEM: 10.4±0.04) and a P-sel IC50 of 39.2 pM (-pIC50±SEM: 10.41±0.04). PAR4 antagonists is potential useful for the development of tools such as radioligands and PET tracers that are not currently available to the field for this target.

Uses

VU0652925, an analog of BMS986120, is a PAR4 antagonist, with IC50 values of 43 pM and 39.2 pM for PAC1 and P-selectin, respectively. VU0652925 is able to suppress GPIIbIIIa activation[1].

References

[1] Matthew T Duvernay, et al. Contributions of Protease-Activated Receptors PAR1 and PAR4 to Thrombin-Induced GPIIbIIIa Activation in Human Platelets. Mol Pharmacol. 2017 Jan;91(1):39-47. DOI:10.1124/mol.116.106666

Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]- Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.		support@targetmol.com	United States	38668	58
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	19904	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	21356	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

View Lastest Price from Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-05-09	VU0652925 1476847-58-1	US $3780.00-5200.00 / mg			10g	TargetMol Chemicals Inc.

VU0652925
1476847-58-1
US $3780.00-5200.00 / mg
TargetMol Chemicals Inc.

1476847-58-1(Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]-)Related Search:

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Imidazo[2,1-b]-1,3,4-thiadiazole, 2-methoxy-6-[6-methoxy-4-[(2-phenyl-4-thiazolyl)methoxy]-2-benzofuranyl]- VU 0652925 VU0652925 VU-0652925 1476847-58-1

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