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ChemicalBook >> CAS DataBase List >>METFORMIN-D6, HYDROCHLORIDE

METFORMIN-D6, HYDROCHLORIDE

CAS No.
1185166-01-1
Chemical Name:
METFORMIN-D6, HYDROCHLORIDE
Synonyms
metformin d6;Diabetosan-d6;Metiguanide-d6;Metformine-D6.HCl;Diabex-d6, Glucophage-d6;Metformin Impurity 9 HCl;METFORMIN-D6, HYDROCHLORIDE;Metformin hydrochloride salt;[2H6]-Metformin hydrochloride;1,1-Dimethyl-d6-biguanide HCl
CBNumber:
CB8649272
Molecular Formula:
C4H6ClD6N5
Molecular Weight:
171.661550668
MDL Number:
MFCD06658649
MOL File:
Mol file
Last updated:2024-11-12 15:22:20

METFORMIN-D6, HYDROCHLORIDE Properties

Melting point 215-218°C
storage temp. -20°C Freezer
solubility Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P264-P270-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/38
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

METFORMIN-D6, HYDROCHLORIDE price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 53183 Metformin-(dimethyl-d6) hydrochloride analytical standard 1185166-01-1 5mg $648 2024-03-01 Buy
Cayman Chemical 16921 Metformin-d6 (hydrochloride) ≥98% deuterated forms (d1-d6) 1185166-01-1 500μg $68 2024-03-01 Buy
Cayman Chemical 16921 Metformin-d6 (hydrochloride) ≥98% deuterated forms (d1-d6) 1185166-01-1 1mg $121 2024-03-01 Buy
Cayman Chemical 16921 Metformin-d6 (hydrochloride) ≥98% deuterated forms (d1-d6) 1185166-01-1 5mg $469 2024-03-01 Buy
TRC M258812 Metformin-d6,Hydrochloride 1185166-01-1 1mg $110 2021-12-16 Buy
Product number Packaging Price Buy
53183 5mg $648 Buy
16921 500μg $68 Buy
16921 1mg $121 Buy
16921 5mg $469 Buy
M258812 1mg $110 Buy

METFORMIN-D6, HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Metformin-d6 is intended for use as an internal standard for the quantification of metformin by GC- or LC-MS. Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day. It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD). Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53-\- human colon cancer mouse xenograft model, but has no effect on HCT116 p53-\- tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I. Formulations containing metformin have been used in the treatment of type 2 diabetes.

Chemical Properties

White Crystalline Solid

Uses

An oral hypoglycemic agent.

METFORMIN-D6, HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 69)Suppliers
Supplier Tel Email Country ProdList Advantage
SIMSON PHARMA LIMITED
+91-8291074273 k.das@simsonpharma.com India 228 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30236 58
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Guangzhou CATO Research Chemicals Inc. 		+86-020-81960175-617 +8615602392859 Intermediate@cato-chem.com China 8322 58
Shandong Huijing bio-pharmaceutical Technology Co. , Ltd. 15192151674 15192151674 1726957134@qq.com China 213 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76

View Lastest Price from METFORMIN-D6, HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Metformin-d6 hydrochloride pictures 2024-11-12 Metformin-d6 hydrochloride
1185166-01-1
 US $93.00-492.00 / mg 98.1% 10g TargetMol Chemicals Inc.
Metformin D6 Hydrochloride pictures 2024-02-29 Metformin D6 Hydrochloride
1185166-01-1
 US $167.00-308.00 / mg 10mg 96% 100 Simson Pharma limited
Metformin-D6 Hydrochloride pictures 2024-02-29 Metformin-D6 Hydrochloride
1185166-01-1
 US $0.00-0.00 / mg 1mg 96% 50 mg Simson Pharma limited

1185166-01-1(METFORMIN-D6, HYDROCHLORIDE)Related Search:

Metformin-(dimethyl-d6) hydrochloride Metformine-D6.HCl [2H6]-Metformin hydrochloride 1,1-Di(methyl-d3)biguanide hydrochloride METFORMIN-D6, HYDROCHLORIDE Diabetosan-d6 Diabex-d6, Glucophage-d6 Metiguanide-d6 N,N-Dimethylimidodicarbonimidic Diamide-d6, Hydrochloride 3-(diaminomethylidene)-1,1-bis(trideuteriomethyl)guanidine,hydrochloride Metformin-d6 hydrochloride (dimethyl-d6) METFORMIN:HCL (DIMETHYL-D6, 99%) 1,1-Dimethyl-d6-biguanide HCl metformin d6 Metformin hydrochloride salt Metformin D6 HydrochlorideQ: What is Metformin D6 Hydrochloride Q: What is the CAS Number of Metformin D6 Hydrochloride Q: What is the storage condition of Metformin D6 Hydrochloride Q: What are the applications of Metformin D6 Hydrochloride 1,1-Dimethylbiguanide-d6 hydrochloride N,N-Di(methyl-d3)-imidodicarbonimidic diamide hydrochloride Metformin Impurity 9 HCl 1185166-01-1 185166-01-1 C4H6D6ClN5 Intermediates & Fine Chemicals Isotope Labeled Compounds Pharmaceuticals Isotope Labelled Compounds