Biotin-Teg-Nh2 Tfa
- CAS No.
- 1334172-59-6
- Chemical Name:
- Biotin-Teg-Nh2 Tfa
- Synonyms
- CAS_1334172-59-6;Biotin-Teg-Nh2 Tfa;Biotin-dPEG??-NH?+TFA-;Biotin-C1-PEG3-C3-amine TFA;Biotin-dPEG??-NH?+TFA- (QBD-10193);1H-Thieno[3,4-d]imidazol-2(3H)-one, 4-[8-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]-5-oxooctyl]tetrahydro-, (3aS,4S,6aR)-, 2,2,2-trifluoroacetate (1:1)
- CBNumber:
- CB84660886
- Molecular Formula:
- C20H38N4O5S.C2HF3O2
- Molecular Weight:
- 545.62
- MDL Number:
- MFCD13184983
- MOL File:
- 1334172-59-6.mol
Biotin-Teg-Nh2 Tfa price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| dPEG | 10193 | Biotin-dPEG??-NH?+TFA- | 1334172-59-6 | 100mg | $100 | 2021-12-16 | Buy |
| AK Scientific | 6190AH | Biotin-Teg-Nh2Tfa | 1334172-59-6 | 25mg | $198 | 2021-12-16 | Buy |
| Iris Biotech GmbH | PEG2110 | Biotin-dPEG?(3)-NH2*TFA | 1334172-59-6 | 100mg | $270 | 2021-12-16 | Buy |
| AK Scientific | 6190AH | Biotin-Teg-Nh2Tfa | 1334172-59-6 | 250mg | $846 | 2021-12-16 | Buy |
| Iris Biotech GmbH | PEG2110 | Biotin-dPEG?(3)-NH2*TFA | 1334172-59-6 | 1g | $1296 | 2021-12-16 | Buy |
Biotin-Teg-Nh2 Tfa Chemical Properties,Uses,Production
Uses
Biotin-C1-PEG3-C3-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Biotin-C1-PEG3-C3-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Biotin-Teg-Nh2 Tfa Preparation Products And Raw materials
Raw materials
Preparation Products
Biotin-Teg-Nh2 Tfa Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32295 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 10203 | 58 |
| Henan Alfachem Co.,Ltd. | 0371-55051623 18137891487 | 2853979817@qq.com | China | 10007 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-66110311 13155353615 | qzhang@aikonchem.com | China | 15525 | 58 |
| Shanghai Jiange Chemical Co., Ltd. | 15921040873 | 1434142450@qq.com | CHINA | 7649 | 58 |
| Shaanxi borno biotechnology co., LTD | +86-13759708231 | asherw9@hotmail.com | China | 2373 | 58 |