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ChemicalBook >> CAS DataBase List >>1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide

1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide

CAS No.
1255516-86-9
Chemical Name:
1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide
Synonyms
MS-1020;MS-1020 >=98% (HPLC);1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphtamide;1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]naphthalene-2-carboxamide;1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide;2-Naphthalenecarboxamide, 1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-
CBNumber:
CB82750655
Molecular Formula:
C21H18N2O3
Molecular Weight:
346.38
MDL Number:
MFCD21363377
MOL File:
1255516-86-9.mol
Last updated:2025-01-27 09:38:02

1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide Properties

storage temp. 2-8°C
solubility DMSO: ≥10mg/mL at 60°C
form powder
color white to tan
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0204 MS-1020 ≥98% (HPLC) 1255516-86-9 25mg $404 2024-03-01 Buy
Sigma-Aldrich SML0204 MS-1020 ≥98% (HPLC) 1255516-86-9 5mg $113 2022-05-15 Buy
Cayman Chemical 14273 MS-1020 ≥95% 1255516-86-9 1mg $93 2024-03-01 Buy
Usbiological 045047 MS-1020 1255516-86-9 1mg $303 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3501-M001 MS-1020 ≥95%(NMR) 1255516-86-9 1mg $65 2021-12-16 Buy
Product number Packaging Price Buy
SML0204 25mg $404 Buy
SML0204 5mg $113 Buy
14273 1mg $93 Buy
045047 1mg $303 Buy
AG-CR1-3501-M001 1mg $65 Buy

1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide Chemical Properties,Uses,Production

Description

MS-1020 is a cell-permeable inhibitor of janus kinase 3 (JAK3), strongly inhibiting constitutive autophosphorylation of JAK3 in L540 cells when used at 30-50 μM. It is without effect on other JAK isoforms and several other kinases, including Src, Lyn, Akt, EGFR, and ERK1/2. Through its effects on JAK3, MS-1020 blocks phosphorylation of downstream signal transduction and activators of transcription isoforms, reducing the expression of anti-apoptotic genes, leading to cell death.

1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide Suppliers

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9804 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44811 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24641 58
Adipogen Life Sciences 41-6192660-40 info@adipogen.com China 5293 58
Cayman Chemical Company 800-3649897 Caymanname@qq.com China 21643 58
1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphtamide 1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide MS-1020 1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]naphthalene-2-carboxamide 2-Naphthalenecarboxamide, 1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]- MS-1020 >=98% (HPLC) 1255516-86-9