SCH 900229
- CAS No.
- 1100361-36-1
- Chemical Name:
- SCH 900229
- Synonyms
- SCH 900229;2H,4H-Pyrano[3,4-c][1]benzopyran, 10b-[(4-chlorophenyl)sulfonyl]-7,10-difluoro-1,4a,5,10b-tetrahydro-4-[2-(methylsulfonyl)ethyl]-, (4S,4aS,10bS)-
- CBNumber:
- CB82667072
- Molecular Formula:
- C21H21ClF2O6S2
- Molecular Weight:
- 506.97
- MDL Number:
- MFCD25977001
- MOL File:
- 1100361-36-1.mol
Last updated:2025-04-17 18:22:24
| FDA UNII | 5RY1XQ9DDH |
|---|
SCH 900229 Chemical Properties,Uses,Production
Uses
SCH 900229 is a potent γ-secretase inhibitor with selective activity against PS1. The Aβ40 IC50 value of SCH 900229 is 1.3 nM, showing its excellent ability in reducing Aβ. SCH 900229 has shown good Aβ-lowering effects after oral administration in preclinical animal models. SCH 900229 has been advanced to human clinical trials for further development of compounds for the inhibition of Alzheimer's disease[1].
References
[1] Discovery of SCH 900229, a Potent Presenilin 1 Selective γ-Secretase Inhibitor for the Treatment of Alzheimer's Disease
SCH 900229 Preparation Products And Raw materials
Raw materials
Preparation Products
SCH 900229 Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19710 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
SCH 900229
2H,4H-Pyrano[3,4-c][1]benzopyran, 10b-[(4-chlorophenyl)sulfonyl]-7,10-difluoro-1,4a,5,10b-tetrahydro-4-[2-(methylsulfonyl)ethyl]-, (4S,4aS,10bS)-
1100361-36-1
C21H21ClF2O6S2